Cyclin-I Recombinant Protein | CCNI recombinant protein

Recombinant Human Cyclin-I

Cat. Num. AAA142812

• Gene Names: CCNI; CYI; CYC1; CCNI1
• Purity: Greater than 85% as determined by SDS-PAGE.
• Synonyms: Cyclin-I; Recombinant Human Cyclin-I; CCNI Human; Cyclin-I Human Recombinant; CCNI; CYC1; CYI; CCNI recombinant protein

• Host: E Coli
• Purity/Purification: Greater than 85% as determined by SDS-PAGE.
• Form/Format: CCNI protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea.; Sterile Filtered clear colorless solution.
• Sequence: MGSSHHHHHH SSGLVPRGSH MGSMKFPGPL ENQRLSFLLE KAITREAQMW KVNVRKMPSN QNVSPSQRDE VIQWLAKLKY QFNLYPETFA LASSLLDRFL ATVKAHPKYL SCIAISCFFL AAKTVEEDER IPVLKVLARD SFCGCSSSEI LRMERIILDK LNWDLHTATP LDFLHIFHAI AVSTRPQLLF SLPKLSPSQH LAVLTKQLLH CMACNQLLQF RGSMLALAMV SLEMEKLIPD WLSLTIELLQ KAQMDSSQLI HCRELVAHHL STLQSSLPLN SVYVYRPLKH TLVTCDKGVF RLHPSSVPGP DFSKDNSKPE VPVRGTAAFY HHLPAASGCK QTSTKRKVEE MEVDDFYDGI KRLYNEDNVS ENVGSVCGTD LSRQEGHASP CPPLQPVSVM.
• Sequence Length: 377

Related Product Information for CCNI recombinant protein

Description: CCNI Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 400 amino acids (1-377 a.a) and having a molecular mass of 44.9kDa.CCNI is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: CCN1 is a part of the extremely conserved cyclin family, whose members are characterized by a remarkable periodicity in protein abundance through the cell cycle. Cyclins which function as regulators of CDK kinases, shows the highest similarity with cyclin G. Different cyclins display diverse expression and degradation patterns which contribute to the chronological coordination of every mitotic event. The transcript of CCN1was found to be expressed continually during cell cycle progression.

Product Categories/Family for CCNI recombinant protein

Protein Kinases; Enzymes; Cyclin

NCBI and Uniprot Product Information

• NCBI GI #: 5802992
• NCBI GeneID: 10983
• NCBI Accession #: NP_006826.1
• NCBI GenBank Nucleotide #: NM_006835.2
• UniProt Accession #: Q14094; B2R6M0; B7Z6X4
• Molecular Weight: 40,877 Da
• NCBI Official Full Name: cyclin-I
• NCBI Official Synonym Full Names: cyclin I
• NCBI Official Symbol: CCNI
• NCBI Official Synonym Symbols: CYI; CYC1; CCNI1
• NCBI Protein Information: cyclin-I; cyclin ITI
• UniProt Protein Name: Cyclin-I
• Protein Family: Cyclin
• UniProt Gene Name: CCNI
• UniProt Entry Name: CCNI_HUMAN

NCBI Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

CCNI: belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined. [provided by RefSeq, Jul 2008]

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 4q21.1

Biological Process: regulation of cell cycle; spermatogenesis