Rabbit anti-Human CCNI Polyclonal Antibody | anti-CCNI antibody

CCNI, CT (CCNI, Cyclin-I) (FITC)

Cat. Num. AAA6282468

• Gene Names: CCNI; CYI; CYC1; CCNI1
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CCNI; Polyclonal Antibody; CT (CCNI; Cyclin-I) (FITC); Cyclin-I; anti-CCNI antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-CCNI antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: CCNI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-331 amino acids from the C-terminal region of human CCNI.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(CCNI Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the CCNI antibody detected the CCNI protein (arrow).)

Related Product Information for anti-CCNI antibody

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined.

Product Categories/Family for anti-CCNI antibody

Antibodies; Cyclin

References

Sun, Z.L., et al. Biochim. Biophys. Acta 1774(6):764-771(2007). Zhu, X., et al. Biochem. Biophys. Res. Commun. 249(1):56-60(1998). Nakamura, T., et al. Exp. Cell Res. 221(2):534-542(1995).

NCBI and Uniprot Product Information

• NCBI GI #: 5802992
• NCBI GeneID: 10983
• NCBI Accession #: NP_006826.1
• NCBI GenBank Nucleotide #: NM_006835.2
• UniProt Accession #: Q14094; B2R6M0; B7Z6X4
• Molecular Weight: 40,877 Da
• NCBI Official Full Name: cyclin-I
• NCBI Official Synonym Full Names: cyclin I
• NCBI Official Symbol: CCNI
• NCBI Official Synonym Symbols: CYI; CYC1; CCNI1
• NCBI Protein Information: cyclin-I; cyclin ITI
• UniProt Protein Name: Cyclin-I
• Protein Family: Cyclin
• UniProt Gene Name: CCNI
• UniProt Entry Name: CCNI_HUMAN

NCBI Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

CCNI: belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined. [provided by RefSeq, Jul 2008]

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 4q21.1

Biological Process: regulation of cell cycle; spermatogenesis