Procalcitonin Recombinant Protein | Calca recombinant protein

Recombinant Mouse Procalcitonin

Cat. Num. AAA140727

• Gene Names: Calca; CA; Ct; Ctn; Calc; Cgrp; CGRP1; Calc1; CGRP-1
• Purity: Purity as determined by densitometric image analysis is greater than 94%.
• Synonyms: Procalcitonin; Recombinant Mouse Procalcitonin; Procalcitonin Mouse; Procalcitonin Mouse Recombinant; Calcitonin; Calca; Calc; Calca recombinant protein

• Host: E Coli
• Purity/Purification: Purity as determined by densitometric image analysis is greater than 94%.
• Form/Format: Procalcitonin was filtered (0.4 um) and lyophilized in 20mM Tris buffer and 50mM NaCl, pH 7.5.; Filtered White lyophilized (freeze-dried) powder.
• Sequence: MKHHHHHHASVPLRSILESS PGMATLSEEE VRLLAALVQD YMQMKARELE QEEEQEAEGS SLDSPRSKRC GNLSTCMLGT YTQDLNKFHT FPQTSIGVEA PGKKRDVAKD LETNHQSHFG N.
• Sequence Length: 136

• Solubility: It is recommended to add 200 ul deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Procalcitonin is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
• Preparation and Storage: Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.

Related Product Information for Calca recombinant protein

Introduction: Procalcitonin is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, an N terminal residue, calcitonin and katacalcin. Levels of unprocessed procalcitonin rise significantly after bacterial infection, trauma or shock.

Description: Procalcitonin Mouse Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain (Val26-Ser136) containing 121 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 13.6kDa.

Product Categories/Family for Calca recombinant protein

Hormones

NCBI and Uniprot Product Information

• NCBI GI #: 779176916
• NCBI GeneID: 12310
• NCBI Accession #: NP_001292545.1
• NCBI GenBank Nucleotide #: NM_001305616.1
• UniProt Accession #: P70160; Q8K1K5; Q99JA0
• Molecular Weight: 14,065 Da
• NCBI Official Full Name: calcitonin gene-related peptide 1 isoform Calca preproprotein
• NCBI Official Synonym Full Names: calcitonin/calcitonin-related polypeptide, alpha
• NCBI Official Symbol: Calca
• NCBI Official Synonym Symbols: CA; Ct; Ctn; Calc; Cgrp; CGRP1; Calc1; CGRP-1
• NCBI Protein Information: calcitonin gene-related peptide 1
• UniProt Protein Name: Calcitonin
• Protein Family: Calcitonin
• UniProt Gene Name: Calca
• UniProt Synonym Gene Names: Calc
• UniProt Entry Name: CALC_MOUSE

Uniprot Description

CALCA: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Belongs to the calcitonin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: axon; cell soma; cytoplasm; extracellular region; extracellular space; intracellular; neuron projection; nucleus; terminal button

Molecular Function: calcitonin receptor binding; receptor binding

Biological Process: adenylate cyclase activation; cellular calcium ion homeostasis; detection of temperature stimulus involved in sensory perception of pain; feeding behavior; G-protein signaling, adenylate cyclase activating pathway; inflammatory response; negative regulation of blood pressure; negative regulation of neurological process; negative regulation of ossification; negative regulation of smooth muscle contraction; neuromuscular junction development; neuropeptide signaling pathway; positive regulation of cell adhesion; positive regulation of ossification; regulation of blood pressure; regulation of heart contraction; regulation of heart rate; regulation of systemic arterial blood pressure by neurological process; response to heat; response to pain; sperm capacitation; vasodilation; vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure