Human chromosome 2 open reading frame 3 ELISA Kit | C2orf3 elisa kit

Human GC-rich sequence DNA-binding factor, C2orf3 ELISA Kit

Cat. Num. AAA9326550

• Gene Names: GCFC2; GCF; TCF9; DNABF; C2orf3
• Reactivity: Human
• Synonyms: chromosome 2 open reading frame 3; Human GC-rich sequence DNA-binding factor; C2orf3 ELISA Kit; Human GC-rich sequence DNA-binding factor (C2orf3) ELISA kit; DNABF; GCF; TCF9; GC bindng factor; hypothetical protein LOC6936; transcription factor 9 (binds GC-rich sequences) ; C2orf3 elisa kit

• Reactivity: Human

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 318083361
• NCBI GeneID: 6936
• NCBI Accession #: NP_001188263.1
• NCBI GenBank Nucleotide #: NM_001201334.1
• UniProt Accession #: P16383; O95032; Q53TY0; Q6P2F2; A4UHQ8
• Molecular Weight: 89,385 Da
• NCBI Official Full Name: GC-rich sequence DNA-binding factor 2 isoform 2
• NCBI Official Synonym Full Names: GC-rich sequence DNA-binding factor 2
• NCBI Official Symbol: GCFC2
• NCBI Official Synonym Symbols: GCF; TCF9; DNABF; C2orf3
• NCBI Protein Information: GC-rich sequence DNA-binding factor 2; TCF-9; GC bindng factor; GC binding factor; transcription factor 9 (binds GC-rich sequences)
• UniProt Protein Name: GC-rich sequence DNA-binding factor 2
• UniProt Gene Name: GCFC2
• UniProt Synonym Gene Names: C2orf3; GCF; TCF9; TCF-9
• UniProt Entry Name: GCFC2_HUMAN

NCBI Description

The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene. [provided by RefSeq, Jul 2008]

Uniprot Description

TCF9: Factor that represses transcription. It binds to the GC- rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Belongs to the GCF family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 2p12

Cellular Component: nucleoplasm; nucleolus; nucleus

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; spliceosome assembly; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent