Mouse Bone morphogenetic protein 7 ELISA Kit | Bmp7 elisa kit

Mouse Bone morphogenetic protein 7 ELISA Kit

Cat. Num. AAA2880566

• Gene Names: Bmp7; OP1
• Reactivity: Mouse
• Synonyms: Bone morphogenetic protein 7; Mouse Bone morphogenetic protein 7 ELISA Kit; BMP-7; Osteogenic protein 1; OP-1; Bmp7; Bmp-7; Op1; Bmp7 elisa kit

• Reactivity: Mouse
• Sequence Length: 430

• Assay Type: Sandwich
• Detection Range: 15.6-1000 pg/mL
• Sensitivity: 8.08 pg/mL
• Intra-Assay CV: <=5.6%
• Inter-Assay CV: <=8.3%
• Recovery: 83%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 31982487
• NCBI GeneID: 12162
• NCBI Accession #: NP_031583.2
• NCBI GenBank Nucleotide #: NM_007557.3
• UniProt Accession #: P23359; Q91XF7
• Molecular Weight: 49,199 Da
• NCBI Official Full Name: bone morphogenetic protein 7 preproprotein
• NCBI Official Synonym Full Names: bone morphogenetic protein 7
• NCBI Official Symbol: Bmp7
• NCBI Official Synonym Symbols: OP1
• NCBI Protein Information: bone morphogenetic protein 7
• UniProt Protein Name: Bone morphogenetic protein 7
• Protein Family: Bone morphogenetic protein
• UniProt Gene Name: Bmp7
• UniProt Synonym Gene Names: Bmp-7; Op1; BMP-7; OP-1
• UniProt Entry Name: BMP7_MOUSE

NCBI Description

This gene encodes a member of a family of secreted factors that participate in developmental signal transduction to stimulate SMAD transcriptional activators. Mutation of this gene results in skeletal, kidney, and other developmental defects. The propeptide is further cleaved into an active chain. [provided by RefSeq, Mar 2013]

Uniprot Description

BMP7: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with TWSG1. Expressed in the kidney and bladder. Lower levels seen in the brain. Belongs to the TGF-beta family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular matrix; extracellular space; vesicle

Molecular Function: cytokine activity; heparin binding; protein binding; transforming growth factor beta receptor binding

Biological Process: anatomical structure formation; axon guidance; BMP signaling pathway; branching morphogenesis of a tube; camera-type eye morphogenesis; cardiac muscle development; cell development; embryonic camera-type eye morphogenesis; embryonic limb morphogenesis; embryonic pattern specification; epithelial cell differentiation; eye development; hindbrain development; kidney development; mesenchymal cell differentiation; mesoderm formation; negative regulation of cell cycle; negative regulation of cell proliferation; negative regulation of MAP kinase activity; negative regulation of mitosis; negative regulation of neurogenesis; negative regulation of neuron differentiation; negative regulation of Notch signaling pathway; negative regulation of phosphorylation; negative regulation of transcription, DNA-dependent; neural fold elevation formation; neurite morphogenesis; odontogenesis of dentine-containing teeth; organ morphogenesis; pattern specification process; pharyngeal system development; positive regulation of apoptosis; positive regulation of bone mineralization; positive regulation of cell differentiation; positive regulation of heterotypic cell-cell adhesion; positive regulation of neuron differentiation; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of MAPKKK cascade; regulation of phosphorylation; salivary gland morphogenesis; steroid hormone mediated signaling; tube morphogenesis; ureteric bud development