ZWILCH blocking peptide
ZWILCH Antibody (C-term) Blocking Peptide
Gene Names
ZWILCH; KNTC1AP; hZwilch
Synonyms
ZWILCH; ZWILCH Antibody (C-term) Blocking Peptide; Protein zwilch homolog; hZwilch; ZWILCH blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
591
Cellular Location
Chromosome, centromere, kinetochore
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ZWILCH blocking peptide
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
54,224 Da
NCBI Official Full Name
Protein zwilch homolog
NCBI Official Synonym Full Names
zwilch kinetochore protein
NCBI Official Symbol
ZWILCH
NCBI Official Synonym Symbols
KNTC1AP; hZwilch
NCBI Protein Information
protein zwilch homolog
UniProt Protein Name
Protein zwilch homolog
Protein Family
UniProt Gene Name
ZWILCH
UniProt Synonym Gene Names
hZwilch
UniProt Entry Name
ZWILC_HUMAN
Uniprot Description
ZWILCH: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Belongs to the ZWILCH family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 15q22.31
Cellular Component: cytosol; kinetochore
Molecular Function: protein binding
Biological Process: mitotic cell cycle checkpoint; sister chromatid cohesion
Research Articles on ZWILCH
Similar Products
Product Notes
The ZWILCH zwilch (Catalog #AAA9223547) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ZWILCH, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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