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ZCRB1 blocking peptide

ZCRB1 Antibody (C-term) Blocking peptide

Gene Names
ZCRB1; MADP1; RBM36; MADP-1; SNRNP31; ZCCHC19
Synonyms
ZCRB1; ZCRB1 Antibody (C-term) Blocking peptide; Zinc finger CCHC-type and RNA-binding motif-containing protein 1; U11/U12 small nuclear ribonucleoprotein 31 kDa protein; U11/U12 snRNP 31 kDa protein; U11/U12-31K; ZCRB1 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
217
Cellular Location
Nucleus, nucleoplasm
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
24,592 Da
NCBI Official Full Name
Zinc finger CCHC-type and RNA-binding motif-containing protein 1
NCBI Official Synonym Full Names
zinc finger CCHC-type and RNA binding motif containing 1
NCBI Official Symbol
ZCRB1
NCBI Official Synonym Symbols
MADP1; RBM36; MADP-1; SNRNP31; ZCCHC19
NCBI Protein Information
zinc finger CCHC-type and RNA-binding motif-containing protein 1
UniProt Protein Name
Zinc finger CCHC-type and RNA-binding motif-containing protein 1
UniProt Gene Name
ZCRB1
UniProt Synonym Gene Names
U11/U12 snRNP 31 kDa protein; U11/U12-31K
UniProt Entry Name
ZCRB1_HUMAN

NCBI Description

Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq, Jul 2008]

Uniprot Description

ZCRB1: Up-regulated by morphine. Down-regulated at 30-36 degrees Celsius while it is up-regulated at 39 degrees Celsius. Component of the U11/U12 snRNPs that are part of the U12- type spliceosome.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 12q12

Cellular Component: nucleoplasm; U12-dependent spliceosome

Molecular Function: RNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing

Research Articles on ZCRB1

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Product Notes

The ZCRB1 zcrb1 (Catalog #AAA9219517) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ZCRB1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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