U2AF1 blocking peptide
U2AF1 Antibody (Center S70) Blocking Peptide
Synonyms
U2AF1; U2AF1 Antibody (Center S70) Blocking Peptide; Splicing factor U2AF 35 kDa subunit; U2 auxiliary factor 35 kDa subunit; U2 small nuclear RNA auxiliary factor 1; U2 snRNP auxiliary factor small subunit; U2AF35; U2AFBP; U2AF1 blocking peptide
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of human U2AF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
240
Cellular Location
Nucleus. Nucleus speckle
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for U2AF1 blocking peptide
Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
19,715 Da
NCBI Official Full Name
Splicing factor U2AF 35 kDa subunit
NCBI Official Synonym Full Names
U2 small nuclear RNA auxiliary factor 1 like 5
NCBI Official Symbol
U2AF1L5
NCBI Protein Information
splicing factor U2AF 35 kDa subunit-like protein
UniProt Protein Name
Splicing factor U2AF 35 kDa subunit
Protein Family
UniProt Gene Name
U2AF1
UniProt Synonym Gene Names
U2AF35; U2AFBP
UniProt Entry Name
U2AF1_HUMAN
Uniprot Description
Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
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Product Notes
The U2AF1 u2af1 (Catalog #AAA9224839) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "U2AF1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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