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TCEAL1 blocking peptide

TCEAL1 (E123) Peptide

Applications
Blocking
Purity
Synthetic peptide TCEAL1 (E123). (Note: the amino acid sequence is proprietary).
The purity is >98%.
Synonyms
TCEAL1; TCEAL1 (E123) Peptide; TCEA-like protein 1; pp21; SIIR; TCEAL1 blocking peptide
Ordering
For Research Use Only!
Specificity
This peptide can be used with studies using MBS3004481 TCEAL1 (E123) pAb.
Purity/Purification
Synthetic peptide TCEAL1 (E123). (Note: the amino acid sequence is proprietary).
The purity is >98%.
Form/Format
1 mg/ml in DI water.
Sequence Length
159
Applicable Applications for TCEAL1 blocking peptide
Blocking
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Related Product Information for TCEAL1 blocking peptide
TCEAL1 (transcription elongation factor A (SII) protein 3), also known as p21, SIIR or pp21, is a member of the TFS-II family. Transcription elongation factors of the TFS-II family are responsible for releasing RNA polymerase II (Pol II) from transcriptional arrest. DNA arresting sites can result in locked ternary complexes if elongating RNA polymerases are trapped. Transcription elongation factors function to activate the intrinsic RNA cleavage activity of RNA polymerases. This allows the RNA polymerase to cleave the nascent transcript, thereby forming a new 3-terminus to resume elongation. TCEAL1 is a 157 amino acid nuclear protein that is ubiquitously expressed. TCEAL1 may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA.

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
transcription elongation factor A protein-like 1
UniProt Protein Name
Transcription elongation factor A protein-like 1
UniProt Gene Name
TCEAL1
UniProt Synonym Gene Names
SIIR; TCEA-like protein 1
UniProt Entry Name
TCAL1_HUMAN

Uniprot Description

SIIR: May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context- dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly. Belongs to the TFS-II family. TFA subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: Xq22.1

Cellular Component: nucleoplasm; nucleus

Molecular Function: transcription factor activity

Biological Process: transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter

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Product Notes

The TCEAL1 tceal1 (Catalog #AAA3004482) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TCEAL1 can be used in a range of immunoassay formats including, but not limited to, Blocking. Researchers should empirically determine the suitability of the TCEAL1 tceal1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TCEAL1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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