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STX7 blocking peptide

STX7 Antibody (N-term) Blocking peptide

Synonyms
STX7; STX7 Antibody (N-term) Blocking peptide; Syntaxin-7; STX7 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
261
Cellular Location
Early endosome membrane; Single-pass type IV membrane protein
Tissue Location
Highest expression is found in placenta followed by heart, skeletal muscle, kidney and brain. Low expression is found in pancreas, lung and liver
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for STX7 blocking peptide
May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,400 Da
NCBI Official Full Name
syntaxin-7 isoform a
NCBI Official Synonym Full Names
syntaxin 7
NCBI Official Symbol
STX7
NCBI Protein Information
syntaxin-7
UniProt Protein Name
Syntaxin-7
Protein Family
UniProt Gene Name
STX7
UniProt Entry Name
STX7_HUMAN

NCBI Description

The protein encoded by this gene is a syntaxin family membrane receptor involved in vesicle transport. The encoded protein binds alpha-SNAP, an important regulator of transport vesicle fusion. Along with syntaxin 13, this protein plays a role in the ordered fusion of endosomes and lysosomes with the phagosome. [provided by RefSeq, May 2016]

Uniprot Description

STX7: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes. Belongs to the syntaxin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Vesicle

Chromosomal Location of Human Ortholog: 6q23.1

Cellular Component: azurophil granule; early endosome; endocytic vesicle; endosome; immunological synapse; integral to membrane; intracellular membrane-bound organelle; late endosome; lysosomal membrane; lysosome; perinuclear region of cytoplasm; plasma membrane; recycling endosome; SNARE complex; vesicle

Molecular Function: chloride channel inhibitor activity; protein binding; SNAP receptor activity; SNARE binding; syntaxin binding

Biological Process: intracellular protein transport; organelle localization; positive regulation of T cell mediated cytotoxicity; vesicle docking; vesicle fusion

Research Articles on STX7

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Product Notes

The STX7 stx7 (Catalog #AAA9225729) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "STX7, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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