Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

ST8SIA4 blocking peptide

ST8SIA4 Antibody (Center) Blocking Peptide

Gene Names
ST8SIA4; PST; PST1; SIAT8D; ST8SIA-IV
Synonyms
ST8SIA4; ST8SIA4 Antibody (Center) Blocking Peptide; CMP-N-acetylneuraminate-poly-alpha-2;8-sialyltransferase; 2499-; Alpha-2;8-sialyltransferase 8D; Polysialyltransferase-1; Sialyltransferase 8D; SIAT8-D; Sialyltransferase St8Sia IV; ST8SiaIV; PST; PST1; SIAT8D; ST8SIA4 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
359
Cellular Location
Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location
Highly expressed in fetal brain, lung and kidney and in adult heart, spleen and thymus. Present to a lesser extent in adult brain, placenta, lung, large and small intestine and peripheral blood leukocytes
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ST8SIA4 blocking peptide
Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
19,260 Da
NCBI Official Full Name
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase
NCBI Official Synonym Full Names
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
NCBI Official Symbol
ST8SIA4
NCBI Official Synonym Symbols
PST; PST1; SIAT8D; ST8SIA-IV
NCBI Protein Information
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase
UniProt Protein Name
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase
Protein Family
UniProt Gene Name
ST8SIA4
UniProt Synonym Gene Names
PST; PST1; SIAT8D; SIAT8-D; ST8SiaIV
UniProt Entry Name
SIA8D_HUMAN

NCBI Description

The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

ST8SIA4: Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells. Belongs to the glycosyltransferase 29 family.

Protein type: Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Membrane protein, integral; EC 2.4.99.-; Transferase

Chromosomal Location of Human Ortholog: 5q21

Cellular Component: Golgi membrane

Molecular Function: alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; sialic acid binding

Biological Process: ganglioside biosynthetic process; N-glycan processing; nervous system development; oligosaccharide metabolic process; protein amino acid glycosylation; protein modification process

Research Articles on ST8SIA4

1. ST8SIA4 gene is involved in the development of multidrug resistance via PI3K/Akt pathway in chronic myeloid leukemia.

Similar Products

ST8SIA4 Antibody

Host: Rabbit
Reactivity: Human
Apps: ELISA, Immunohistochemistry

ST8SIA4 Recombinant Protein

Host: E Coli or Yeast or Baculovirus or Mammalian Cell
Reactivity: n/a
Apps: n/a

ST8SIA4 Antibody

Host: Rabbit
Reactivity: Human, Mouse, Rat
Apps: Western Blot, Immunohistochemistry

ST8SIA4 Antibody

Host: Rabbit
Reactivity: Human, Rat
Apps: Western Blot

Product Notes

The ST8SIA4 st8sia4 (Catalog #AAA9228392) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ST8SIA4, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

aaabiotech.com © 2012-2025

All rights reserved.

Contact us by

Tel: +1 (619) 604-9440 | Fax: +1 (619) 604-9440
contact@aaabiotech.com
Looking for a specific manual?
Request a Manual