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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7046671 at dilution 1:100)

Rabbit anti-Human ST8SIA4 Polyclonal Antibody | anti-ST8SIA4 antibody

ST8SIA4 Antibody

Gene Names
ST8SIA4; PST; PST1; SIAT8D; ST8SIA-IV
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
ST8SIA4; Polyclonal Antibody; ST8SIA4 Antibody; CMP-N-acetylneuraminate-poly-alpha-2; 8-sialyltransferase; Alpha-2; 8-sialyltransferase 8D; Polysialyltransferase-1; Sialyltransferase 8D; SIAT8-D; Sialyltransferase St8Sia IV; ST8SiaIV; PST; PST1; SIAT8D; anti-ST8SIA4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
359
Applicable Applications for anti-ST8SIA4 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC: 1:20-1:200
Species
Human
Immunogen
Recombinant human CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase protein (20-168AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-109048 / sc-68896
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7046671 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7046671 at dilution 1:100)
Related Product Information for anti-ST8SIA4 antibody
Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,260 Da
NCBI Official Full Name
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase isoform a
NCBI Official Synonym Full Names
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
NCBI Official Symbol
ST8SIA4
NCBI Official Synonym Symbols
PST; PST1; SIAT8D; ST8SIA-IV
NCBI Protein Information
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase
UniProt Protein Name
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase
UniProt Gene Name
ST8SIA4
UniProt Synonym Gene Names
PST; PST1; SIAT8D; SIAT8-D; ST8SiaIV
UniProt Entry Name
SIA8D_HUMAN

NCBI Description

The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

ST8SIA4: Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells. Belongs to the glycosyltransferase 29 family.

Protein type: EC 2.4.99.-; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Membrane protein, integral; Transferase

Chromosomal Location of Human Ortholog: 5q21

Cellular Component: Golgi membrane

Molecular Function: alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; sialic acid binding

Biological Process: ganglioside biosynthetic process; N-glycan processing; nervous system development; oligosaccharide metabolic process; protein amino acid glycosylation; protein modification process

Research Articles on ST8SIA4

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Product Notes

The ST8SIA4 st8sia4 (Catalog #AAA7046671) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ST8SIA4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ST8SIA4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC: 1:20-1:200. Researchers should empirically determine the suitability of the ST8SIA4 st8sia4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ST8SIA4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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