Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

SMPD4 blocking peptide

SMPD4 Antibody (N-term) Blocking peptide

Gene Names
SMPD4; NET13; NSMASE3; NSMASE-3
Synonyms
SMPD4; SMPD4 Antibody (N-term) Blocking peptide; Sphingomyelin phosphodiesterase 4; Neutral sphingomyelinase 3; nSMase-3; nSMase3; Neutral sphingomyelinase III; KIAA1418; SMPD4 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
837
Cellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein
Tissue Location
Widely expressed, with highest levels in heart and skeletal muscle.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for SMPD4 blocking peptide
Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
60,173 Da
NCBI Official Full Name
sphingomyelin phosphodiesterase 4 isoform 1
NCBI Official Synonym Full Names
sphingomyelin phosphodiesterase 4
NCBI Official Symbol
SMPD4
NCBI Official Synonym Symbols
NET13; NSMASE3; NSMASE-3
NCBI Protein Information
sphingomyelin phosphodiesterase 4
UniProt Protein Name
Sphingomyelin phosphodiesterase 4
UniProt Gene Name
SMPD4
UniProt Synonym Gene Names
KIAA1418; nSMase-3; nSMase3
UniProt Entry Name
NSMA3_HUMAN

NCBI Description

Sphingomyelinases (EC 3.1.4.12), such as SMPD4, catalyze the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide (Krut et al., 2006 [PubMed 16517606]).[supplied by OMIM, Mar 2008]

Uniprot Description

SMPD4: Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; EC 3.1.4.12; Phosphodiesterase; Endoplasmic reticulum; Lipid Metabolism - sphingolipid

Chromosomal Location of Human Ortholog: 2q21.1

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; trans-Golgi network

Molecular Function: sphingomyelin phosphodiesterase activity; sphingomyelin phosphodiesterase D activity

Biological Process: ceramide biosynthetic process; glycerophospholipid catabolic process; glycosphingolipid metabolic process; sphingomyelin catabolic process

Research Articles on SMPD4

Similar Products

Product Notes

The SMPD4 smpd4 (Catalog #AAA9225842) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SMPD4, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.