Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SMPD4 antibody.)
Rabbit anti-Human, Mouse SMPD4 Polyclonal Antibody | anti-SMPD4 antibody
SMPD4 Polyclonal Antibody
Gene Names
SMPD4; SKNY; NET13; NSMASE3; NSMASE-3
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Affinity Purification
Synonyms
SMPD4; Polyclonal Antibody; SMPD4 Polyclonal Antibody; EC 3.1.4.12; EC=3.1.4.123; FLJ20297; FLJ20756; KIAA1418; NET 13; NET13; Neutral sphingomyelinase 3; Neutral sphingomyelinase III; NSMA3; nSMase 3; nSMase-3; nSMase3; OTTHUMP00000162391; OTTHUMP00000190862; SKNY protein; smpd4; Sphingomyelin phosphodiesterase 4; neutral membrane (neutral sphingomyelinase 3); anti-SMPD4 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration
1 mg/mL (varies by lot)
Sequence Length
837
Applicable Applications for anti-SMPD4 antibody
Western Blot (WB)
Application Notes
WB: 1:200-1:2000
Immunogen
Recombinant protein of human SMPD4
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SMPD4 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SMPD4 antibody.)
Related Product Information for anti-SMPD4 antibody
The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network.
Product Categories/Family for anti-SMPD4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated: 44kDa, 56-69kDa, 83-98kDa
Observed: 100kDa
Observed: 100kDa
NCBI Official Full Name
sphingomyelin phosphodiesterase 4 isoform 3
NCBI Official Synonym Full Names
sphingomyelin phosphodiesterase 4
NCBI Official Symbol
SMPD4
NCBI Official Synonym Symbols
SKNY; NET13; NSMASE3; NSMASE-3
NCBI Protein Information
sphingomyelin phosphodiesterase 4
UniProt Protein Name
Sphingomyelin phosphodiesterase 4
Protein Family
UniProt Gene Name
SMPD4
UniProt Synonym Gene Names
nSMase-31 PublicationManual assertion based on opinion iniRef.1; nSMase31 PublicationManual assertion based on opinion iniRef.1
NCBI Description
The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network. [provided by RefSeq, Mar 2017]
Uniprot Description
Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide (PubMed:16517606). May sensitize cells to DNA damage-induced apoptosis (PubMed:18505924).
Research Articles on SMPD4
Similar Products
Product Notes
The SMPD4 smpd4 (Catalog #AAA2555705) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SMPD4 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SMPD4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:200-1:2000. Researchers should empirically determine the suitability of the SMPD4 smpd4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SMPD4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
