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SIM1 blocking peptide

SIM1 Antibody (N-term) Blocking peptide

Gene Names
SIM1; bHLHe14
Synonyms
SIM1; SIM1 Antibody (N-term) Blocking peptide; Single-minded homolog 1; Class E basic helix-loop-helix protein 14; bHLHe14; BHLHE14; SIM1 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
766
Cellular Location
Nucleus
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for SIM1 blocking peptide
Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
85,515 Da
NCBI Official Full Name
Single-minded homolog 1
NCBI Official Synonym Full Names
single-minded family bHLH transcription factor 1
NCBI Official Symbol
SIM1
NCBI Official Synonym Symbols
bHLHe14
NCBI Protein Information
single-minded homolog 1
UniProt Protein Name
Single-minded homolog 1
Protein Family
UniProt Gene Name
SIM1
UniProt Synonym Gene Names
BHLHE14; bHLHe14
UniProt Entry Name
SIM1_HUMAN

NCBI Description

SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome. [provided by RefSeq, Jul 2008]

Uniprot Description

SIM1: Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 6q16.3

Molecular Function: transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter

Disease: Obesity

Research Articles on SIM1

Similar Products

Product Notes

The SIM1 sim1 (Catalog #AAA9219541) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SIM1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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