RAB3A blocking peptide
RAB3A Antibody (N-term) Blocking Peptide
NCBI and Uniprot Product Information
Uniprot Description
RAB3A: Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. Heterodimer with RIMS2. Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3A. Interacts with the exocyst complex through SEC15. Binds SYTL4, RIMS1 and RIMS2. Interacts with RAB3IP. Interacts with SGSM1 and SGSM3. Specifically expressed in brain. Belongs to the small GTPase superfamily. Rab family.
Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: axon; plasma membrane; synaptic vesicle; terminal button
Molecular Function: GTPase activity; myosin V binding; protein binding
Biological Process: constitutive secretory pathway; glutamate secretion; neurotransmitter secretion; positive regulation of exocytosis; regulation of short-term neuronal synaptic plasticity; regulation of synaptic vesicle fusion to presynaptic membrane; synaptic vesicle exocytosis
Research Articles on RAB3A
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Product Notes
The RAB3A rab3a (Catalog #AAA9221127) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RAB3A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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