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RAB3A blocking peptide

RAB3A Antibody (N-term) Blocking Peptide

Synonyms
RAB3A; RAB3A Antibody (N-term) Blocking Peptide; Ras-related protein Rab-3A; RAB3A blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
220
Cellular Location
Cell membrane; Lipid-anchor; Cytoplasmic side
Tissue Location
Specifically expressed in brain.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for RAB3A blocking peptide
Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
24,984 Da
NCBI Official Full Name
Ras-related protein Rab-3A
NCBI Official Synonym Full Names
RAB3A, member RAS oncogene family
NCBI Official Symbol
RAB3A
NCBI Protein Information
ras-related protein Rab-3A
UniProt Protein Name
Ras-related protein Rab-3A
Protein Family
UniProt Gene Name
RAB3A
UniProt Entry Name
RAB3A_HUMAN

Uniprot Description

RAB3A: Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. Heterodimer with RIMS2. Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3A. Interacts with the exocyst complex through SEC15. Binds SYTL4, RIMS1 and RIMS2. Interacts with RAB3IP. Interacts with SGSM1 and SGSM3. Specifically expressed in brain. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: axon; plasma membrane; synaptic vesicle; terminal button

Molecular Function: GTPase activity; myosin V binding; protein binding

Biological Process: constitutive secretory pathway; glutamate secretion; neurotransmitter secretion; positive regulation of exocytosis; regulation of short-term neuronal synaptic plasticity; regulation of synaptic vesicle fusion to presynaptic membrane; synaptic vesicle exocytosis

Research Articles on RAB3A

Similar Products

Product Notes

The RAB3A rab3a (Catalog #AAA9221127) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RAB3A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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