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PTPLAD1 blocking peptide

PTPLAD1 Antibody (N-term) Blocking Peptide

Gene Names
HACD3; BIND1; B-IND1; HSPC121; PTPLAD1
Synonyms
PTPLAD1; PTPLAD1 Antibody (N-term) Blocking Peptide; Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3; 3-hydroxyacyl-CoA dehydratase 3; HACD3; Butyrate-induced protein 1; B-ind1; hB-ind1; Protein tyrosine phosphatase-like protein PTPLAD1; Protein-tyrosine phosphatase-like A domain-containing protein 1; BIND1; PTPLAD1 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
362
Cellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location
Highly expressed in testis, kidney, brain, liver and weakly in skeletal muscle, spleen and heart. No expression detected in leukocytes.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PTPLAD1 blocking peptide
Responsible for the dehydration step in very long-chain fatty acid (VLCFA) synthesis. Involved in Rac1-signaling pathways leading to the modulation of gene expression.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
36,431 Da
NCBI Official Full Name
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
NCBI Official Synonym Full Names
3-hydroxyacyl-CoA dehydratase 3
NCBI Official Symbol
HACD3
NCBI Official Synonym Symbols
BIND1; B-IND1; HSPC121; PTPLAD1
NCBI Protein Information
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
UniProt Protein Name
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
UniProt Gene Name
HACD3
UniProt Synonym Gene Names
hB-ind1
UniProt Entry Name
HACD3_HUMAN

Uniprot Description

PTPLAD1: induced by sodium butyrate treatment. A downstream mediator of the monomeric GTPase RAC1.

Protein type: Membrane protein, integral; EC 4.2.1.134; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 15q22.2

Cellular Component: cytoplasm; endoplasmic reticulum; focal adhesion; mitochondrion; nuclear membrane

Molecular Function: 3-hydroxyacyl-CoA dehydratase activity; enzyme binding; GTPase activator activity; protein binding

Biological Process: activation of JNK activity; fatty acid elongation; positive regulation of viral genome replication; positive regulation of viral protein levels in host cell; small GTPase mediated signal transduction; very-long-chain fatty acid biosynthetic process

Research Articles on PTPLAD1

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Product Notes

The PTPLAD1 hacd3 (Catalog #AAA9223827) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PTPLAD1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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