Western Blot (WB)
(PTPLAD1 Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PTPLAD1 antibody detected the PTPLAD1 protein (arrow).)
Rabbit PTPLAD1 Polyclonal Antibody | anti-PTPLAD1 antibody
PTPLAD1 Antibody (N-term)
Gene Names
HACD3; BIND1; B-IND1; HSPC121; PTPLAD1
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PTPLAD1; Polyclonal Antibody; PTPLAD1 Antibody (N-term); Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3; 3-hydroxyacyl-CoA dehydratase 3; HACD3; Butyrate-induced protein 1; B-ind1; hB-ind1; Protein tyrosine phosphatase-like protein PTPLAD1; Protein-tyrosine phosphatase-like A domain-containing protein 1; BIND1; anti-PTPLAD1 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PTPLAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-58 amino acids from the N-terminal region of human PTPLAD1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.34 (varies by lot)
Sequence Positions
32-58
Sequence Length
362
Applicable Applications for anti-PTPLAD1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(PTPLAD1 Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PTPLAD1 antibody detected the PTPLAD1 protein (arrow).)
Western Blot (WB)
(PTPLAD1 Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PTPLAD1 antibody detected the PTPLAD1 protein (arrow).)
Related Product Information for anti-PTPLAD1 antibody
Responsible for the dehydration step in very long-chain fatty acids (VLCFAs) synthesis. Involved in Rac1-signaling pathways leading to the modulation of gene expression.
Product Categories/Family for anti-PTPLAD1 antibody
References
Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)
Taguwa, S., et al. J. Virol. 83(20):10427-10436(2009)
Taguwa, S., et al. J. Virol. 82(6):2631-2641(2008)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Sabbah, M., et al. Gene 374, 128-133 (2006) :
Taguwa, S., et al. J. Virol. 83(20):10427-10436(2009)
Taguwa, S., et al. J. Virol. 82(6):2631-2641(2008)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Sabbah, M., et al. Gene 374, 128-133 (2006) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43160
NCBI Official Full Name
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
NCBI Official Synonym Full Names
3-hydroxyacyl-CoA dehydratase 3
NCBI Official Symbol
HACD3
NCBI Official Synonym Symbols
BIND1; B-IND1; HSPC121; PTPLAD1
NCBI Protein Information
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
UniProt Protein Name
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
UniProt Gene Name
HACD3
UniProt Synonym Gene Names
hB-ind1
UniProt Entry Name
HACD3_HUMAN
Uniprot Description
PTPLAD1: induced by sodium butyrate treatment. A downstream mediator of the monomeric GTPase RAC1.
Protein type: EC 4.2.1.134; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 15q22.2
Cellular Component: endoplasmic reticulum membrane; focal adhesion; endoplasmic reticulum; integral to membrane
Molecular Function: protein binding; enzyme binding; 3-hydroxyacyl-CoA dehydratase activity; GTPase activator activity
Biological Process: I-kappaB kinase/NF-kappaB cascade; positive regulation of viral genome replication; small GTPase mediated signal transduction; very-long-chain fatty acid biosynthetic process; Rac protein signal transduction; fatty acid elongation; positive regulation of viral protein levels in host cell; activation of JNK activity; Rho protein signal transduction; positive regulation of GTPase activity
Research Articles on PTPLAD1
Similar Products
Product Notes
The PTPLAD1 hacd3 (Catalog #AAA9210976) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 32-58. The PTPLAD1 Antibody (N-term) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's PTPLAD1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the PTPLAD1 hacd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTPLAD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
