Prkaca/Prkacb Blocking Peptide | Prkacb blocking peptide
Mouse Prkaca/Prkacb Antibody (C-term) Blocking Peptide
Gene Names
Prkacb; CbPKA; Pkacb
Synonyms
Prkaca/Prkacb; Mouse Prkaca/Prkacb Antibody (C-term) Blocking Peptide; cAMP-dependent protein kinase catalytic subunit beta; PKA C-beta; Prkacb; Pkacb; Prkacb blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
351
Cellular Location
Cytoplasm. Cell membrane. Nucleus. Note: Translocates into the nucleus (monomeric catalytic subunit). The inactive holoenzyme is found in the cytoplasm.
Tissue Location
Isoform 1 is found in all tissues examined, with the highest expression in the brain and very low levels in the testis. Isoform 2 is strongly expressed in the brain, in the prelimbic and insular cortex. Isoform 3 is also found only in the brain, but at very low levels.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for Prkacb blocking peptide
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
46,014 Da
NCBI Official Full Name
cAMP-dependent protein kinase catalytic subunit beta
NCBI Official Synonym Full Names
protein kinase, cAMP dependent, catalytic, beta
NCBI Official Symbol
Prkacb
NCBI Official Synonym Symbols
CbPKA; Pkacb
NCBI Protein Information
cAMP-dependent protein kinase catalytic subunit beta
UniProt Protein Name
cAMP-dependent protein kinase catalytic subunit beta
Protein Family
UniProt Gene Name
Prkacb
UniProt Synonym Gene Names
Pkacb; PKA C-beta
UniProt Entry Name
KAPCB_MOUSE
Uniprot Description
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis ().
Research Articles on Prkacb
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Product Notes
The Prkacb prkacb (Catalog #AAA9220800) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Prkaca/Prkacb, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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