PHF12 blocking peptide
PHF12 Peptide
Gene Names
PHF12; PF1
Applications
Western Blot
Synonyms
PHF12; PHF12 Peptide; PHF12 blocking peptide
Form/Format
Lyophilized powder
Sequence Length
1004
Applicable Applications for PHF12 blocking peptide
Western Blot (WB)
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Related Product Information for PHF12 blocking peptide
This is a synthetic peptide designed for use in combination with anti-PHF12 antibody made
Target Description: PHF12 acts as a transcriptional repressor. It is involved in recruitment of functional SIN3A complexes to DNA. PHF12 represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). IT may also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA.
Target Description: PHF12 acts as a transcriptional repressor. It is involved in recruitment of functional SIN3A complexes to DNA. PHF12 represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). IT may also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA.
Product Categories/Family for PHF12 blocking peptide
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
110kDa
NCBI Official Full Name
PHD finger protein 12 isoform 1
NCBI Official Synonym Full Names
PHD finger protein 12
NCBI Official Symbol
PHF12
NCBI Official Synonym Symbols
PF1
NCBI Protein Information
PHD finger protein 12
UniProt Protein Name
PHD finger protein 12
Protein Family
UniProt Gene Name
PHF12
UniProt Synonym Gene Names
KIAA1523; Pf1
UniProt Entry Name
PHF12_HUMAN
Uniprot Description
Function: Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA. Ref.1
Subunit structure: Isoform 2 interacts with SIN3A in a complex composed of HDAC1, SAP30 and SIN3A. Interacts with AES. Ref.1
Subcellular location: Nucleus Ref.1.
Domain: The polybasic region (PBR) is responsive to the binding to phosphoinositides (PtdInsPs).
Sequence similarities: Contains 1 FHA domain.Contains 2 PHD-type zinc fingers.
Similar Products
Product Notes
The PHF12 phf12 (Catalog #AAA3234883) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PHF12 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the PHF12 phf12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PHF12, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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