MSL2 blocking peptide
MSL2 Antibody (N-term) Blocking Peptide
Gene Names
MSL2; MSL-2; MSL2L1; RNF184
Synonyms
MSL2; MSL2 Antibody (N-term) Blocking Peptide; E3 ubiquitin-protein ligase MSL2; 632-; Male-specific lethal 2-like 1; MSL2-like 1; Male-specific lethal-2 homolog; MSL-2; Male-specific lethal-2 homolog 1; RING finger protein 184; KIAA1585; MSL2L1; RNF184; MSL2 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
577
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for MSL2 blocking peptide
Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
54,339 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase MSL2
NCBI Official Synonym Full Names
male-specific lethal 2 homolog (Drosophila)
NCBI Official Symbol
MSL2
NCBI Official Synonym Symbols
MSL-2; MSL2L1; RNF184
NCBI Protein Information
E3 ubiquitin-protein ligase MSL2
UniProt Protein Name
E3 ubiquitin-protein ligase MSL2
Protein Family
UniProt Gene Name
MSL2
UniProt Synonym Gene Names
KIAA1585; MSL2L1; RNF184; MSL2-like 1; MSL-2
UniProt Entry Name
MSL2_HUMAN
Uniprot Description
MSL2: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Belongs to the MSL2 family.
Protein type: Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 3q22.3
Cellular Component: nucleoplasm
Research Articles on MSL2
Similar Products
Product Notes
The MSL2 msl2 (Catalog #AAA9222504) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MSL2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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