Mouse macrophage inflammatory protein 3beta, MIP-3beta (Cat number does not match description) ELISA Kit | CCL19 elisa kit
Mouse macrophage inflammatory protein 3beta, MIP-3beta (Cat number does not match description) ELISA Kit
Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with Mouse ADP antibody. ADP present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse ADP Antibody is added and binds to ADP in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated ADP antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse ADP. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
NCBI and Uniprot Product Information
NCBI Description
This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014]
Uniprot Description
May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
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Product Notes
The Mouse CCL19 ccl19 (Catalog #AAA164244) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA164244 ELISA Kit recognizes Mouse CCL19. It is sometimes possible for the material contained within the vial of "macrophage inflammatory protein 3beta, MIP-3beta (Cat number does not match description), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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