MLN64 blocking peptide

MLN64 Blocking Peptide

Cat. Num. AAA9621856

• Gene Names: STARD3; CAB1; es64; MLN64
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: MLN64; MLN64 Blocking Peptide; CAB 1; CAB1; Es 64; Es64; FLJ41370; Metastatic lymph node gene 64 protein; Metastatic lymph node protein 64; MLN 64; Mln64; Protein CAB 1; Protein CAB1; Protein MLN 64; Protein MLN64; StAR related lipid transfer protein 3; StAR-related lipid transfer protein 3; STAR3_HUMAN; STARD 3; StARD3; START domain containing 3; START domain-containing protein 3; Steroidogenic acute regulatory protein related; MLN64 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for MLN64 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for MLN64 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 116242802
• NCBI GeneID: 10948
• UniProt Accession #: Q14849; Q53Y53; Q96HM9; A8MXA4; B4DUY1; F5H0G2
• Molecular Weight: 445
• NCBI Official Full Name: StAR-related lipid transfer protein 3
• NCBI Official Synonym Full Names: StAR-related lipid transfer (START) domain containing 3
• NCBI Official Symbol: STARD3
• NCBI Official Synonym Symbols: CAB1; es64; MLN64
• NCBI Protein Information: stAR-related lipid transfer protein 3; MLN 64; metastatic lymph node protein 64; START domain-containing protein 3; metastatic lymph node gene 64 protein; steroidogenic acute regulatory protein related
• UniProt Protein Name: StAR-related lipid transfer protein 3
• Protein Family: MLN64 N-terminal domain
• UniProt Gene Name: STARD3
• UniProt Synonym Gene Names: CAB1; MLN64; MLN 64; StARD3
• UniProt Entry Name: STAR3_HUMAN

NCBI Description

This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

Uniprot Description

STARD3: Binds and transports cholesterol. Promotes steroidogenesis in placenta and brain. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q11-q12

Cellular Component: mitochondrion; late endosome membrane; lysosomal membrane; cytoplasm; integral to membrane

Molecular Function: protein binding; cholesterol transporter activity; cholesterol binding

Biological Process: steroid metabolic process; cholesterol metabolic process; progesterone biosynthetic process; cholesterol transport; lipid metabolic process; mitochondrial transport