Mouse anti-Human STARD3 Monoclonal Antibody | anti-STARD3 antibody

STARD3 (CAB1, MLN64, StAR-related Lipid Transfer Protein 3, Metastatic Lymph Node Gene 64 Protein, Protein CAB1, START Domain-containing Protein 3, FLJ41370)

Cat. Num. AAA6008623

• Gene Names: STARD3; CAB1; es64; MLN64
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: STARD3; Monoclonal Antibody; STARD3 (CAB1; MLN64; StAR-related Lipid Transfer Protein 3; Metastatic Lymph Node Gene 64 Protein; Protein CAB1; START Domain-containing Protein 3; FLJ41370); Anti -STARD3 (CAB1; anti-STARD3 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone Number: 1D1
• Specificity: Recognizes human STARD3.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MSKLPRELTRDLERSLPAVASLGSSLSHSQSLSSHLLPPPEKRRAISDVRRTFCLFVTFDLLFISLLWIIELNTNTGIRKNLEQEIIQYNFKTSFFDIFVLAFFRFSGLLLGYAVLQLRHWWVIAVTTLVSSAFLIVKVILSELLSKGAFGYLLPIVSFVLAWLETWFLDFKVLPQEAEEERWYLAAQVAVARGPLLFSGALSEGQFYSPPESFAGSDNESDEEVAGKKSFSAQEREYIRQGKEATAVVDQILAQEENWKFEKNNEYGDTVYTIEVPFHGKTFILKTFLPCPAELVYQEVILQPERMVLWNKTVTACQILQRVEDNTLISYDVSAGAAGGVVSPRDFVNVRRIERRRDRYLSSGIATSHSAKPPTHKYVRGENGPGGFIVLKSASNPRVCTFVWILNTDLKGRLPRYLIHQSLAATMFEFAFHLRQRISELGARA

• Applicable Applications for anti-STARD3 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in ELISA and Western Blot.; Dilution: Sandwich ELISA: The detection limit for recombinant GST tagged STARD3 is 0.3ng/ml as a capture antibody.
• Immunogen: Full length recombinant corresponding to aa1-446 from human STARD3 (AAH08747) with GST tag. MW of the GST tag alone is 26kD.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of STARD3 (MBS6008623) expression in transfected 293T cell line by STARD3 monoclonal antibody.|Lane 1: STARD3 transfected lysate (50.5kD).|Lane 2: Non-transfected lysate.)

Testing Data

(Detection limit for recombinant GST tagged STARD3 is 0.3ng/ml as a capture antibody (MBS6008623).)

Related Product Information for anti-STARD3 antibody

This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.

Product Categories/Family for anti-STARD3 antibody

Antibodies; Abs to Lipoproteins

NCBI and Uniprot Product Information

• NCBI GI #: 260763906
• NCBI GeneID: 10948
• NCBI Accession #: NP_001159410.1
• NCBI GenBank Nucleotide #: NM_001165938.1
• UniProt Accession #: Q14849; Q53Y53; Q96HM9; A8MXA4; B4DUY1; F5H0G2
• Molecular Weight: 50,502 Da
• NCBI Official Full Name: stAR-related lipid transfer protein 3 isoform 3
• NCBI Official Synonym Full Names: StAR-related lipid transfer (START) domain containing 3
• NCBI Official Symbol: STARD3
• NCBI Official Synonym Symbols: CAB1; es64; MLN64
• NCBI Protein Information: stAR-related lipid transfer protein 3; MLN 64; metastatic lymph node protein 64; START domain-containing protein 3; metastatic lymph node gene 64 protein; steroidogenic acute regulatory protein related
• UniProt Protein Name: StAR-related lipid transfer protein 3
• Protein Family: StAR-related lipid transfer protein
• UniProt Gene Name: STARD3
• UniProt Synonym Gene Names: CAB1; MLN64; MLN 64; StARD3
• UniProt Entry Name: STAR3_HUMAN

NCBI Description

This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

Uniprot Description

STARD3: Binds and transports cholesterol. Promotes steroidogenesis in placenta and brain. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17q11-q12

Cellular Component: mitochondrion; late endosome membrane; lysosomal membrane; cytoplasm; integral to membrane

Molecular Function: protein binding; cholesterol transporter activity; cholesterol binding

Biological Process: steroid metabolic process; cholesterol metabolic process; progesterone biosynthetic process; cholesterol transport; lipid metabolic process; mitochondrial transport