Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug Hela cell Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 20 seconds)
Rabbit anti-Human KIF2A Polyclonal Antibody | anti-KIF2A antibody
KIF2A Antibody
Immunohistochemistry: 1:100-1:300
Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug Hela cell Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 20 seconds)
Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug Hela cell Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 20 seconds)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human placenta tissue using at dilution 1/70.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human placenta tissue using at dilution 1/70.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a plus end-directed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Uniprot Description
KIF2A: Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity. Belongs to the kinesin-like protein family. MCAK/KIF2 subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Motor; Microtubule-binding
Chromosomal Location of Human Ortholog: 5q12-q13
Cellular Component: spindle pole; centrosome; kinesin complex; membrane; spindle microtubule; cytosol
Molecular Function: protein binding; microtubule binding; ATPase activity; motor activity; microtubule motor activity; ATP binding
Biological Process: nervous system development; mitotic spindle organization and biogenesis; cell division; metabolic process; microtubule depolymerization; antigen processing and presentation of exogenous peptide antigen via MHC class II; mitotic cell cycle; blood coagulation; cell differentiation; microtubule-based movement
Disease: Cortical Dysplasia, Complex, With Other Brain Malformations 3
Research Articles on KIF2A
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Product Notes
The KIF2A kif2a (Catalog #AAA9400873) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KIF2A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KIF2A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:200-1:1000 Immunohistochemistry: 1:100-1:300. Researchers should empirically determine the suitability of the KIF2A kif2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KIF2A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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