HEMGN blocking peptide
HEMGN Blocking Peptide (C-term)
Gene Names
HEMGN; NDR; EDAG; CT155; EDAG-1
Synonyms
HEMGN; HEMGN Blocking Peptide (C-term); Hemogen; Erythroid differentiation-associated gene protein; EDAG-1; Hemopoietic gene protein; Negative differentiation regulator protein; EDAG; NDR; HEMGN blocking peptide
Specificity
The synthetic peptide sequence is selected from aa 355-369 of HUMAN HEMGN
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
484
Cellular Location
Nucleus.
Tissue Location
Expressed in hematopoietic precursor cells, thyroid and spermatids (at protein level). Expressed in bone marrow, testis, thymus. Expressed in prostate cancer and ovarian cancer. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for HEMGN blocking peptide
Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
55,341 Da
NCBI Official Full Name
Hemogen
NCBI Official Synonym Full Names
hemogen
NCBI Official Symbol
HEMGN
NCBI Official Synonym Symbols
NDR; EDAG; CT155; EDAG-1
NCBI Protein Information
hemogen
UniProt Protein Name
Hemogen
Protein Family
UniProt Gene Name
HEMGN
UniProt Synonym Gene Names
EDAG; NDR; EDAG-1
UniProt Entry Name
HEMGN_HUMAN
Uniprot Description
HEMGN: Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 9q22.33
Cellular Component: nucleoplasm
Molecular Function: protein binding
Biological Process: regulation of osteoblast differentiation
Research Articles on HEMGN
Similar Products
Product Notes
The HEMGN hemgn (Catalog #AAA9229688) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "HEMGN, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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