ATP6V0A2 blocking peptide

ATP6V0A2 Blocking Peptide

Cat. Num. AAA9620342

• Gene Names: ATP6V0A2; A2; RTF; TJ6; WSS; ARCL; J6B7; STV1; TJ6M; TJ6S; VPH1; ARCL2A; ATP6A2; ATP6N1D
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: ATP6V0A2; ATP6V0A2 Blocking Peptide; a2; A2V ATPase; ARCL; ATP6a2; ATP6N1D; ATPase; H+ transporting; lysosomal V0 subunit a isoform 2; lysosomal V0 subunit a2; Infantile malignant osteopetrosis; J6B7; Lysosomal H(+) transporting ATPase V0 subunit a2; Lysosomal H(+)-transporting ATPase V0 subunit a2; regeneration and tolerance factor; Stv1; TJ6; TJ6M; TJ6s; V ATPase 116 kDa isoform a2; V type proton ATPase 116 kDa subunit a; V type proton ATPase 116 kDa subunit a isoform 2; V-ATPase 116 kDa isoform a2; V-type proton ATPase 116 kDa subunit a isoform 2; Vacuolar proton translocating ATPase 116 kDa subunit a; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2; Vph1; VPP2_HUMAN; WSS; ATP6V0A2 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for ATP6V0A2 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for ATP6V0A2 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 42741679
• NCBI GeneID: 23545
• NCBI Accession #: NP_036595.2
• NCBI GenBank Nucleotide #: NM_012463.3
• UniProt Accession #: Q9Y487; Q6NUM0; A8K026
• Molecular Weight: 98,082 Da
• NCBI Official Full Name: V-type proton ATPase 116 kDa subunit a isoform 2
• NCBI Official Synonym Full Names: ATPase, H+ transporting, lysosomal V0 subunit a2
• NCBI Official Symbol: ATP6V0A2
• NCBI Official Synonym Symbols: A2; RTF; TJ6; WSS; ARCL; J6B7; STV1; TJ6M; TJ6S; VPH1; ARCL2A; ATP6A2; ATP6N1D
• NCBI Protein Information: V-type proton ATPase 116 kDa subunit a isoform 2; A2V-ATPase; v-ATPase 116 kDa; regeneration and tolerance factor; v-type proton ATPase 116 kDa subunit a; lysosomal H(+)-transporting ATPase V0 subunit a2; vacuolar proton translocating ATPase 116 kDa subun
• UniProt Protein Name: V-type proton ATPase 116 kDa subunit a isoform 2
• Protein Family: V-type proton ATPase
• UniProt Gene Name: ATP6V0A2
• UniProt Synonym Gene Names: V-ATPase 116 kDa isoform a2
• UniProt Entry Name: VPP2_HUMAN

NCBI Description

The protein encoded by this gene is a subunit of the vacuolar ATPase (v-ATPase), an heteromultimeric enzyme that is present in intracellular vesicles and in the plasma membrane of specialized cells, and which is essential for the acidification of diverse cellular components. V-ATPase is comprised of a membrane peripheral V(1) domain for ATP hydrolysis, and an integral membrane V(0) domain for proton translocation. The subunit encoded by this gene is a component of the V(0) domain. Mutations in this gene are a cause of both cutis laxa type II and wrinkly skin syndrome. [provided by RefSeq, Jul 2009]