ART1 blocking peptide

ART1 Antibody (N-term) Blocking Peptide

• Gene Names: ART1; RT6; ART2; ARTC1; CD296
• Synonyms: ART1; ART1 Antibody (N-term) Blocking Peptide; GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1; ADP-ribosyltransferase C2 and C3 toxin-like 1; ARTC1; Mono(ADP-ribosyl)transferase 1; CD296; ART1 blocking peptide

• Specificity: The synthetic peptide sequence used to generate the antibody was selected from the N-term region of human ART1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
• Form/Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
• Sequence Length: 327

• Cellular Location: Sarcoplasmic reticulum membrane; Lipid- anchor, GPI-anchor
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for ART1 blocking peptide

Has ADP-ribosyltransferase activity toward GLP1R.

NCBI and Uniprot Product Information

• NCBI GI #: 206729882
• NCBI GeneID: 417
• UniProt Accession #: P52961; Q6NTD2; Q96KT9
• Molecular Weight: 36,335 Da
• NCBI Official Full Name: GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
• NCBI Official Synonym Full Names: ADP-ribosyltransferase 1
• NCBI Official Symbol: ART1
• NCBI Official Synonym Symbols: RT6; ART2; ARTC1; CD296
• NCBI Protein Information: GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
• UniProt Protein Name: GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
• Protein Family: Arrestin family protein
• UniProt Gene Name: ART1
• UniProt Synonym Gene Names: ARTC1
• UniProt Entry Name: NAR1_HUMAN

NCBI Description

ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008]

Uniprot Description

ART1: Has ADP-ribosyltransferase activity toward GLP1R. Belongs to the Arg-specific ADP-ribosyltransferase family.

Protein type: EC 2.4.2.31; Membrane protein, GPI anchor; Transferase

Chromosomal Location of Human Ortholog: 11p15

Cellular Component: integral to plasma membrane; plasma membrane