GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 Recombinant Protein | ART1 recombinant protein

Recombinant Human GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1

Cat. Num. AAA968352

• Gene Names: ART1; RT6; ART2; ARTC1; CD296
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1; Recombinant Human GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1; ADP-ribosyltransferase C2 and C3 toxin-like 1; ARTC1; Mono(ADP-ribosyl)transferase 1; CD296; ART1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 23-295. Full Length of Mature Protein
• Sequence: QSHPITRRDLFSQEIQLDMALASFDDQYAGCAAAMTAALPDLNHTEFQANQVYADSWTLASSQWQERQARWPEWSLSPTRPSPPPLGFRDEHGVALLAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLGSGQRPPRCHQVFRGVHGLRFRPAGPRATVRLGGFASASLKHVAAQQFGEDTFFGIWTCLGAPIKGYSFFPGEEEVLIPPFETFQVINASRLAQGPARIYLRALGKHSTYNCEYIKDKKCKSGPCHLDNS

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for ART1 recombinant protein

Has ADP-ribosyltransferase activity toward GLP1R.

Product Categories/Family for ART1 recombinant protein

Epigenetics and Nuclear Signaling

References

Immunological and structural conservation of mammalian skeletal muscle glycosylphosphatidylinositol-linked ADP-ribosyltransferases.Okazaki I.J., Zolkiewska A., Nightingale M.S., Moss J.Biochemistry 33:12828-12836(1994)

NCBI and Uniprot Product Information

• NCBI GI #: 158634472
• NCBI GeneID: 417
• NCBI Accession #: NP_004305.2
• NCBI GenBank Nucleotide #: NM_004314.2
• UniProt Accession #: P52961; Q6NTD2; Q96KT9
• Molecular Weight: 32.5 kDa
• NCBI Official Full Name: GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
• NCBI Official Synonym Full Names: ADP-ribosyltransferase 1
• NCBI Official Symbol: ART1
• NCBI Official Synonym Symbols: RT6; ART2; ARTC1; CD296
• NCBI Protein Information: GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
• UniProt Protein Name: GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
• Protein Family: GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase
• UniProt Gene Name: ART1
• UniProt Synonym Gene Names: ARTC1
• UniProt Entry Name: NAR1_HUMAN

NCBI Description

ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008]

Uniprot Description

ART1: Has ADP-ribosyltransferase activity toward GLP1R. Belongs to the Arg-specific ADP-ribosyltransferase family.

Protein type: EC 2.4.2.31; Membrane protein, GPI anchor; Transferase

Chromosomal Location of Human Ortholog: 11p15

Cellular Component: cell surface; integral to plasma membrane; plasma membrane; sarcoplasmic reticulum membrane

Molecular Function: NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity

Biological Process: innate immune response; protein amino acid ADP-ribosylation