ARFGAP3 blocking peptide

ARFGAP3 Antibody (C-term) Blocking Peptide

• Gene Names: ARFGAP3; ARFGAP1
• Synonyms: ARFGAP3; ARFGAP3 Antibody (C-term) Blocking Peptide; ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 3; ARFGAP1; ARFGAP3 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 516

• Cellular Location: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note: Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment
• Tissue Location: Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for ARFGAP3 blocking peptide

GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.

NCBI and Uniprot Product Information

• NCBI GI #: 21263420
• NCBI GeneID: 26286
• UniProt Accession #: Q9NP61; Q9BSC6; Q9H9J0; Q9NT10; Q9NUP5; Q9Y4V3; Q9Y4V4; E9PB03
• Molecular Weight: 51,990 Da
• NCBI Official Full Name: ADP-ribosylation factor GTPase-activating protein 3
• NCBI Official Synonym Full Names: ADP ribosylation factor GTPase activating protein 3
• NCBI Official Symbol: ARFGAP3
• NCBI Official Synonym Symbols: ARFGAP1
• NCBI Protein Information: ADP-ribosylation factor GTPase-activating protein 3
• UniProt Protein Name: ADP-ribosylation factor GTPase-activating protein 3
• Protein Family: ADP-ribosylation factor GTPase-activating protein
• UniProt Gene Name: ARFGAP3
• UniProt Synonym Gene Names: ARFGAP1; ARF GAP 3
• UniProt Entry Name: ARFG3_HUMAN

NCBI Description

The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008]

Uniprot Description

GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.