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CNO Blocking Peptide | BLOC1S4 blocking peptide

CNO Blocking Peptide (Center)

Gene Names
BLOC1S4; CNO; BLOS4; BCAS4L
Synonyms
CNO; CNO Blocking Peptide (Center); Biogenesis of lysosome-related organelles complex 1 subunit 4; BLOC-1 subunit 4; Protein cappuccino homolog; BLOC1S4; BLOC1S4 blocking peptide
Ordering
Specificity
The synthetic peptide sequence is selected from aa 129-143 of Human BLOC1S4
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
217
Cellular Location
Cytoplasm.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for BLOC1S4 blocking peptide
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
23,351 Da
NCBI Official Full Name
Biogenesis of lysosome-related organelles complex 1 subunit 4
NCBI Official Synonym Full Names
biogenesis of lysosomal organelles complex 1 subunit 4
NCBI Official Symbol
BLOC1S4
NCBI Official Synonym Symbols
CNO; BLOS4; BCAS4L
NCBI Protein Information
biogenesis of lysosome-related organelles complex 1 subunit 4
UniProt Protein Name
Biogenesis of lysosome-related organelles complex 1 subunit 4
UniProt Gene Name
BLOC1S4
UniProt Synonym Gene Names
CNO; BLOC-1 subunit 4
UniProt Entry Name
BL1S4_HUMAN

NCBI Description

This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and is a model for Hermansky-Pudlak syndrome. The encoded protein may play a role in intracellular vesicular trafficking. [provided by RefSeq, Jul 2008]

Uniprot Description

CNO: The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking. Belongs to the cappuccino family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 4p16.1

Cellular Component: cytoplasm; cytosol

Molecular Function: protein binding

Biological Process: anterograde axon cargo transport; anterograde synaptic vesicle transport; intracellular transport; neurite development

Research Articles on BLOC1S4

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Product Notes

The BLOC1S4 bloc1s4 (Catalog #AAA9229102) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CNO, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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