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Western Blot (WB) (CNO Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CNO antibody detected the CNO protein (arrow).)

Rabbit anti-Human CNO Polyclonal Antibody | anti-BLOC1S4 antibody

CNO Antibody (Center)

Gene Names
BLOC1S4; CNO; BLOS4; BCAS4L
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CNO; Polyclonal Antibody; CNO Antibody (Center); Biogenesis of lysosome-related organelles complex 1 subunit 4; BLOC-1 subunit 4; Protein cappuccino homolog; BLOC1S4; anti-BLOC1S4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CNO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the Central region of human CNO.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
114-143
Sequence Length
217
Applicable Applications for anti-BLOC1S4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(CNO Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CNO antibody detected the CNO protein (arrow).)

Western Blot (WB) (CNO Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CNO antibody detected the CNO protein (arrow).)
Related Product Information for anti-BLOC1S4 antibody
The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking (By similarity).
Product Categories/Family for anti-BLOC1S4 antibody
References
Ota T., et al. Nat. Genet. 36:40-45(2004).
Hillier L.W., et al. Nature 434:724-731(2005).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23351
NCBI Official Full Name
biogenesis of lysosome-related organelles complex 1 subunit 4
NCBI Official Synonym Full Names
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
NCBI Official Symbol
BLOC1S4
NCBI Official Synonym Symbols
CNO; BLOS4; BCAS4L
NCBI Protein Information
biogenesis of lysosome-related organelles complex 1 subunit 4
UniProt Protein Name
Biogenesis of lysosome-related organelles complex 1 subunit 4
UniProt Gene Name
BLOC1S4
UniProt Synonym Gene Names
CNO; BLOC-1 subunit 4
UniProt Entry Name
BL1S4_HUMAN

NCBI Description

This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and is a model for Hermansky-Pudlak syndrome. The encoded protein may play a role in intracellular vesicular trafficking. [provided by RefSeq, Jul 2008]

Uniprot Description

CNO: The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking. Belongs to the cappuccino family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 4p16.1

Cellular Component: cytoplasm; cytosol

Molecular Function: protein binding

Biological Process: melanosome organization and biogenesis; anterograde synaptic vesicle transport; post-Golgi vesicle-mediated transport; neuromuscular process controlling balance; anterograde axon cargo transport; neurite development

Research Articles on BLOC1S4

Similar Products

Product Notes

The BLOC1S4 bloc1s4 (Catalog #AAA9201417) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 114-143. The CNO Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CNO can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the BLOC1S4 bloc1s4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNO, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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