Structure
SPV 106 Biochemical
SPV 106
Purity
>98% (HPLC)
Synonyms
SPV 106; Pentadecylidenemalonate 1b; SPV 106 biochemical
Purity/Purification
>98% (HPLC)
Target
HAT
Receptor
HAT
Chemical Name
Pentadecylidenemalonate 1b
SMILES
O=C([O-])/C(C([O-])=O)=C/CCCCCCCCCCCCCC
Molecular Formula
C18H30O42
CAS Number
1036939-38-4
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for SPV 106 biochemical
SPV 106 is the first mixed activator/inhibitor of Histone acetyltransferases (HATs), potentiates p300/CBP-associated factor (PCAF) HAT activity while inhibiting those of p300/CBP and recombinant CBP; significantly increases the H3 acetylation level in U937 cells, but no detectable effect on the acetylation level of the non-histone substrate a-tubulin; restores normal levels of H3K9Ac and H3K14Ac, reduces DNA CpG hypermethylation, and recovers D-CMSC proliferation and differentiation, enhances memory for fear extinction and prevents fear renewal in mice.
Product Categories/Family for SPV 106 biochemical
References
1. Sbardella G, et al. Bioorg Med Chem Lett. 2008 May 1; 18 (9):2788-92.
2. Wei W, et al. J Neurosci. 2012 Aug 29; 32 (35):11930-41.
3. Vecellio M, et al. Diabetes. 2014 Jun; 63 (6):2132-47.
4. Castellano S, et al. ChemMedChem. 2015 Jan; 10 (1):144-57.
2. Wei W, et al. J Neurosci. 2012 Aug 29; 32 (35):11930-41.
3. Vecellio M, et al. Diabetes. 2014 Jun; 63 (6):2132-47.
4. Castellano S, et al. ChemMedChem. 2015 Jan; 10 (1):144-57.
Similar Products
Product Notes
The SPV 106 (Catalog #AAA3600183) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SPV 106, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
