Structure
PU-141, Inhibitor
PU-141
Purity
>98% (HPLC)
Synonyms
PU-141; PU141; PU 141; inhibitor
Purity/Purification
>98% (HPLC)
Target
HAT
Receptor
HAT
Chemical Name
2-(4-(trifluoromethyl)benzyl)isothiazolo[5, 4-b]pyridin-3(2H)-one
SMILES
O=C1N(CC2=CC=C(C(F)(F)F)C=C2)SC3=NC=CC=C31
Molecular Formula
C14H9F3N2OS
CAS Number
168334-34-7
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for PU-141, inhibitor
PU-141 is a potent, selective CBP/p300 inhibitor that inhibits SK-N-SH cell growth with GI50 of 0.48uM; blocks growth of SK-N-SH neuroblastoma xenografts in mice, also reduces histone lysine acetylation in vivo at concentrations that block neoplastic xenograft growth.
Product Categories/Family for PU-141, inhibitor
References
1. Gajer JM, et al. Oncogenesis. 2015 Feb 9; 4:e137.
2. Furdas SD, et al. Bioorg Med Chem. 2011 Jun 15; 19 (12):3678-89.
2. Furdas SD, et al. Bioorg Med Chem. 2011 Jun 15; 19 (12):3678-89.
Similar Products
Product Notes
The PU-141 (Catalog #AAA3602570) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PU-141, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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