Structure
MKC-733 Biochemical
MKC-733
Purity
>98% (HPLC)
Synonyms
MKC-733; MKC733; Pumosetrag; DDP 733; MKC-733 biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 30mg/mL (88.28mM)
Target
5-HT Receptor
Receptor
5-HT Receptor
Chemical Name
Thieno[3, 2-b]pyridine-6-carboxamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4, 7-dihydro-7-oxo-, monohydrochloride(9CI)
SMILES
O=C(C1=CNC(C=CS2)=C2C1=O)N[C@H]3CN4CCC3CC4.[H]Cl
Molecular Formula
C15H18ClN3O2S
CAS Number
194093-42-0
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for MKC-733 biochemical
A potent, selective, orally active 5-HT3 receptor agonist with high affinity for canine intestinal smooth muscle 5-HT3 receptors; dose dependently stimulates contraction and basal electrolyte secretion in the isolated guinea pig colon, effects that are antagonized by the selective 5-HT3 antagonist ondansetron, also accelerates gastric emptying in some animal models. Irritable Bowel Syndrome Phase 2 Discontinued
Product Categories/Family for MKC-733 biochemical
References
1. Coleman NS, et al. Aliment Pharmacol Ther. 2003 Nov 15; 18 (10):1039-48.
2. Fujita T, et al.
3. Chetty N, et al. Pharmacology. 2008; 81 (2):104-9.
4. Choung RS, et al. Neurogastroenterol Motil. 2014 Jan; 26 (1):13-20.
2. Fujita T, et al.
3. Chetty N, et al. Pharmacology. 2008; 81 (2):104-9.
4. Choung RS, et al. Neurogastroenterol Motil. 2014 Jan; 26 (1):13-20.
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Product Notes
The MKC-733 (Catalog #AAA3603042) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MKC-733, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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