Structure
LM11A-31 Biochemical
LM11A-31
Purity
>98% (HPLC)
Synonyms
LM11A-31; LM11A 31; LM11A-31 biochemical
Purity/Purification
>98% (HPLC)
Target
Trk Receptor
Receptor
Trk Receptor
Chemical Name
(2S, 3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide
Molecular Formula
C12H25N3O2
CAS Number
102562-74-3
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for LM11A-31 biochemical
An orally available, brain penetrant p75NTR ligand that blocks p75-mediated cell death, also increases proliferation and survival of hippocampal neural progenitors; shows no effect on nerve growth factor (NGF) binding to TrkA; prevents and reverses atrophy of cholinergic neurites, as well as reversing AD pathologies in mid- to late-stage AD mice models. Alzheimer Disease Phase 2 Clinical
Product Categories/Family for LM11A-31 biochemical
References
1. Massa SM, et al. J Neurosci. 2006 May 17; 26 (20):5288-300.
2. Meeker RB, et al. J Neuroimmune Pharmacol. 2012 Jun; 7 (2):388-400.
3. Simmons DA, et al. PLoS One. 2014 Aug 25; 9 (8):e102136.
4. Meeker RB, et al. Exp Neurol. 2016 Jan; 275 Pt 1:182-98.
2. Meeker RB, et al. J Neuroimmune Pharmacol. 2012 Jun; 7 (2):388-400.
3. Simmons DA, et al. PLoS One. 2014 Aug 25; 9 (8):e102136.
4. Meeker RB, et al. Exp Neurol. 2016 Jan; 275 Pt 1:182-98.
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Product Notes
The LM11A-31 (Catalog #AAA3600118) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "LM11A-31, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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