Structure
CGP-42112 Biochemical
CGP-42112
Purity
>98% (HPLC)
Synonyms
CGP-42112; CGP42112; CGP 42112; CGP-42112A; CGP-42112 biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=350mg/mL
Target
Angiotensin Receptor
Receptor
Angiotensin Receptor
Chemical Name
L-Isoleucine, N-(3-pyridinylcarbonyl)-L-tyrosyl-N6-[N2-[(phenylmethoxy)carbonyl]-L-arginyl]-L-lysyl-L-histidyl-L-prolyl
SMILES
CC[C@H](C)[C@@H](C(O)=O)NC([C@H]1N(C([C@H](CC2=CNC=N2)NC([C@H](CCCCNC([C@H](CCCNC(N)=N)NC(OCC3=CC=CC=C3)=O)=O)NC([C@H](CC4=CC=C(O)C=C4)NC(C5=CC=CN=C5)=O)=O)=O)=O)CCC1)=O
Molecular Formula
C52H69N13O11
CAS Number
127060-75-7
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for CGP-42112 biochemical
CGP-42112 (CGP42112A) is a highly potent, selective Angiotensin-II subtype 2 receptor (AT2 receptor) agonist with Ki of 0.24nM; significantly inhibits cGMP production from the basal value, also significantly inhibits TH-enzyme activity from the basal value in cultured porcine adrenal medullary cells; antagonizes Ang-II induced contractions in rabbit aortic rings with IC50 of 1.85uM.
Product Categories/Family for CGP-42112 biochemical
References
1. Hakam AC, et al. Am J Physiol Renal Physiol. 2006 Jun; 290 (6):F1430-6.
2. Takekoshi K, et al. Biochem Biophys Res Commun. 2000 Jun 7; 272 (2):544-50.
3. Nveri L, et al. J Cereb Blood Flow Metab. 1994 Jan; 14 (1):38-44.
4. Nveri L, et al. Acta Physiol Scand Suppl. 1995; 630:1-48.
2. Takekoshi K, et al. Biochem Biophys Res Commun. 2000 Jun 7; 272 (2):544-50.
3. Nveri L, et al. J Cereb Blood Flow Metab. 1994 Jan; 14 (1):38-44.
4. Nveri L, et al. Acta Physiol Scand Suppl. 1995; 630:1-48.
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Product Notes
The CGP-42112 (Catalog #AAA3601134) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CGP-42112, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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