Structure
AZD 9272 Biochemical
AZD 9272
Purity
>98% (HPLC)
Synonyms
AZD 9272; AZD9272; AZD-9272; AZD 9272 biochemical
Purity/Purification
>98% (HPLC)
Target
mGluR
Receptor
mGluR
Chemical Name
3-fluoro-5-(3-(5-fluoropyridin-2-yl)-1, 2, 4-oxadiazol-5-yl)benzonitrile
SMILES
N#CC1=CC(C2=NC(C3=NC=C(F)C=C3)=NO2)=CC(F)=C1
Molecular Formula
C14H6F2N4O
CAS Number
327056-26-8
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for AZD 9272 biochemical
A potent, selective, highly CNS-penetrant and orally availablemgluR5 negative allosteric modulator Kd of 2.8nM; does not elicit any agonist, antagonist or positive allosteric modulator on any of the other sevenmgluR subtypes at 30uM; completely reverses the glutamate-stimulated phosphatidyl inositol hydrolysis in humanmgluR5-GHEK cells with IC50 of 26nM, causes psychoactive effects selectively mediated bymgluR5 mechanisms in vivo, Pain Phase 1 Discontinued
Product Categories/Family for AZD 9272 biochemical
References
1. Raboisson P, et al. Bioorg Med Chem Lett. 2012 Nov 15; 22 (22):6974-9.
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Product Notes
The AZD 9272 (Catalog #AAA3604062) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "AZD 9272, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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