Structure
AMTB hydrochloride Biochemical
AMTB hydrochloride
Purity
0.99
Synonyms
AMTB hydrochloride; N- (3-aminopropyl)-2-[ (3-methylphenyl) methoxy]-N- (thiophen-2-ylmethyl) benzamide; hydrochloride; N- (3-aminopropyl)-2-[ (3-methylphenyl) methoxy]-N- (2-thienylmethyl)-benzamide; monohydrochloride; N- (3-aminopropyl)-2- ( (3-methylbenzyl) oxy)-N- (thiophen-2-ylmethyl) benzamide hydrochloride; AMTB hydrochloride biochemical
Purity/Purification
0.99
Form/Format
Solid
Solubility
~40 mg/ml in water and DMSO
Molecular Formula
C??H??ClN?O?S
CAS Number
926023-82-7
PubChem CID
16095383
SMILES
CC1=CC (=CC=C1)COC2=CC=CC=C2C (=O)N (CCCN)CC3=CC=CS3.Cl
InChi
InChI=1S/C23H26N2O2S.ClH/c1-18-7-4-8-19 (15-18)17-27-22-11-3-2-10-21 (22)23 (26)25 (13-6-12-24)16-20-9-5-14-28-20;/h2-5,7-11,14-15H,6,12-13,16-17,24H2,1H3;1H
InChi Key
UDXGBANGPYONOK-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Shelf life: ~36 months
Structure
Structure
Related Product Information for AMTB hydrochloride biochemical
AMTB is an antagonist of transient receptor potential melastatin 8 (TRPM8). It inhibits icilin-induced calcium influx with a pIC50 of 6.23. Intravenous administration of AMTB (3 mg/kg) decreases the frequency of volume-induced urinary bladder contractions, without reducing the amplitude of contraction in a rat model. It inhibits the response to noxious bladder stimulation at 10 mg/kg. AMTB also inhibits the sodium channel (Nav) isoforms Nav1.1-1.9 with IC50 values of 2 uM-14.8 uM and decreases viability of MDA-MB-231 and SK-BR-3 breast cancer cells with IC50 values of ~23.7 uM and 17.3 uM, respectively in a TRPM8-independent manner.
Product Categories/Family for AMTB hydrochloride biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/16095383
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Product Notes
The AMTB hydrochloride (Catalog #AAA849073) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "AMTB hydrochloride, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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