Structure
AMG-510 Biochemical
AMG-510
Purity
>=98% by HPLC
Synonyms
AMG-510; AMG 510; 4- ( (S)-4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7- (2-fluoro-6-hydroxyphenyl)-1- (2-isopropyl-4-methylpyridin-3-yl) pyrido[2; 3-d]pyrimidin-2 (1H)-one; AMG510; AMG-510 biochemical
Purity/Purification
>=98% by HPLC
Form/Format
White to off-white solid
Solubility
in DMSO
Molecular Formula
C??H??F?N?O?
CAS Number
2252403-56-6
PubChem CID
384641292
SMILES
O=C (C=C)N1C[C@H] (C)N (C2=NC (N (C3=C (C)C=CN=C3C (C)C)C4=C2C=C (F)C (C5=C (O)C=CC=C5F)=N4)=O)CC1
InChi
InChI=1S/C30H30F2N6O3/c1-6-23 (40)36-12-13-37 (18 (5)15-36)28-19-14-21 (32)26 (24-20 (31)8-7-9-22 (24)39)34-29 (19)38 (30 (41)35-28)27-17 (4)10-11-33-25 (27)16 (2)3/h6-11,14,16,18,39H,1,12-13,15H2,2-5H3/t18-/m0/s1
InChi Key
NXQKSXLFSAEQCZ-SFHVURJKSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Shelf life: ~36 months
Structure
Structure
Related Product Information for AMG-510 biochemical
AMG-510 is an orally available agent that targets the specific KRAS mutation, p.G12C, with potential antineoplastic activity. Upon oral administration, KRAS mutant-targeting AMG-510 selectively targets the KRAS p.G12C mutant, at either the DNA, RNA or protein level, and prevents the expression of and/or tumor cell signaling through the KRAS p.G12C mutant. This may inhibit growth in KRAS p.G12C-expressing tumor cells.
Product Categories/Family for AMG-510 biochemical
References
https://pubchem.ncbi.nlm.nih.gov/substance/384641292
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Product Notes
The AMG-510 (Catalog #AAA848830) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "AMG-510, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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