Typical Testing Data/Standard Curve (for reference only)
MMP-3 assay kit
MMP-3 Inhibitor Screening Kit (Fluorometric)
Gene Names
mmp3; sl-1; stmy; str1; chds6; mmp-3; mmp10; stmy1
Synonyms
MMP-3; MMP-3 Inhibitor Screening Kit (Fluorometric); MMP-3 assay kit
Sequence Length
497
Samples
Test inhibitors for MMP-3
Features & Benefits
Simple procedure; takes ~ 35-45 minutes
Fast and convenient
The assay is simple, reliable and ensures accuracy and consistency when working with multiple samples.
Fast and convenient
The assay is simple, reliable and ensures accuracy and consistency when working with multiple samples.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for MMP-3 assay kit
Product Information: MMP-3 Inhibitor Screening Kit: High-Throughput Suitable Fluorometric Assay to Screen MMP-3 Inhibitors within 50 min.. Simple, Sensitive, and Reliable. Includes Inhibitor Control, GM6001. 100 Assays.
Background: The matrix metalloproteinase-3 (MMP-3, stromelysin-1) exhibits a number of activities that would make it a particularly good tumor promoter. Like several other MMPs, MMP-3 was first cloned and later recloned as a cancer-specific gene. In addition to degrading numerous extracellular matrix components, MMP-3 can activate gelatinase B, the collagenases and several serpin-type serine proteinase inhibitors. Moreover, it can release a number of cell surface molecules, including E-cadherin, a known contributor to cancer development. In MyBioSource's MMP-3 Inhibitor Screening Assay Kit, MMP-3 hydrolyzes a specific FRET substrate to release the quenched fluorescent group Mca, which can be detected fluorometrically at Em/Ex=325/393 nm. The kit provides a rapid, simple, sensitive, and reliable test suitable as a high throughput screening assay of MMP-3 inhibition. In addition, we also offer a human recombinant MMP-3 enzyme (MyBioSource #7783) and a MMP-3 Activity Assay Kit (MyBioSource #K783-100), separately.
Summary: Detection method- Fluorescence (Ex/Em 325/393 nm)
Applications- The kit can be used to screen inhibitors of MMP-3.
Background: The matrix metalloproteinase-3 (MMP-3, stromelysin-1) exhibits a number of activities that would make it a particularly good tumor promoter. Like several other MMPs, MMP-3 was first cloned and later recloned as a cancer-specific gene. In addition to degrading numerous extracellular matrix components, MMP-3 can activate gelatinase B, the collagenases and several serpin-type serine proteinase inhibitors. Moreover, it can release a number of cell surface molecules, including E-cadherin, a known contributor to cancer development. In MyBioSource's MMP-3 Inhibitor Screening Assay Kit, MMP-3 hydrolyzes a specific FRET substrate to release the quenched fluorescent group Mca, which can be detected fluorometrically at Em/Ex=325/393 nm. The kit provides a rapid, simple, sensitive, and reliable test suitable as a high throughput screening assay of MMP-3 inhibition. In addition, we also offer a human recombinant MMP-3 enzyme (MyBioSource #7783) and a MMP-3 Activity Assay Kit (MyBioSource #K783-100), separately.
Summary: Detection method- Fluorescence (Ex/Em 325/393 nm)
Applications- The kit can be used to screen inhibitors of MMP-3.
Product Categories/Family for MMP-3 assay kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
matrix metallopeptidase 3
NCBI Official Synonym Full Names
matrix metallopeptidase 3
NCBI Official Symbol
mmp3
NCBI Official Synonym Symbols
sl-1; stmy; str1; chds6; mmp-3; mmp10; stmy1
NCBI Protein Information
matrix metallopeptidase 3
Similar Products
Product Notes
The MMP-3 (Catalog #AAA841450) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MMP-3, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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