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Western Blot (WB) (Western blot analysis Defensin alpha4 using HuvEc whole cell lysates)

Defensin alpha4 Antibody | anti-DEFA4 antibody

Defensin alpha4 Antibody

Gene Names
DEFA4; HP4; DEF4; HP-4; HNP-4
Synonyms
Defensin alpha4; Defensin alpha4 Antibody; anti-DEFA4 antibody
Ordering
For Research Use Only!
Sequence Length
97

Western Blot (WB)

(Western blot analysis Defensin alpha4 using HuvEc whole cell lysates)

Western Blot (WB) (Western blot analysis Defensin alpha4 using HuvEc whole cell lysates)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,504 Da
NCBI Official Full Name
neutrophil defensin 4 preproprotein
NCBI Official Synonym Full Names
defensin alpha 4
NCBI Official Symbol
DEFA4
NCBI Official Synonym Symbols
HP4; DEF4; HP-4; HNP-4
NCBI Protein Information
neutrophil defensin 4
UniProt Protein Name
Neutrophil defensin 4
Protein Family
UniProt Gene Name
DEFA4
UniProt Synonym Gene Names
DEF4; HP-4

NCBI Description

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Oct 2014]

Uniprot Description

Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production.

Research Articles on DEFA4

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Product Notes

The DEFA4 defa4 (Catalog #AAA8517643) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Defensin alpha4, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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