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Western Blot (WB)
(Western Blot analysis of 293T cells with Phospho-eIF4B (Ser422) Polyclonal Antibody at dilution of 1:2000)
Translation Initiation Complex Antibody Kit
Translation Initiation Complex Antibody Sampler Kit
Applications
Western Blot
Synonyms
Translation Initiation Complex; Translation Initiation Complex Antibody Sampler Kit; Translation Initiation Complex antibody kit
Applicable Applications for Translation Initiation Complex antibody kit
Western Blot (WB)
Western Blot (WB)
(Western Blot analysis of 293T cells with Phospho-eIF4B (Ser422) Polyclonal Antibody at dilution of 1:2000)
Western Blot (WB)
(Western Blot analysis of 293T cells with Phospho-eIF4B (Ser422) Polyclonal Antibody at dilution of 1:2000)
Western Blot (WB)
(Western Blot analysis of COS7 cells using eIF4E Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of COS7 cells using eIF4E Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of 293 cells with Phospho-eIF4E (Ser209) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of 293 cells with Phospho-eIF4E (Ser209) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of Lovo and 293T cell using EIF4G1 Polyclonal Antibody at dilution of 1:450)
Western Blot (WB)
(Western Blot analysis of Lovo and 293T cell using EIF4G1 Polyclonal Antibody at dilution of 1:450)
Related Product Information for Translation Initiation Complex antibody kit
Background: Avariety of factors contribute to the important biological event of translation initiation. The Eukaryotic initiation Factor 4E (eIF4E) complex of translation initiation factors binds to the 5' m7 GTP cap to open up the mRNA secondary structure and allow small ribosome subunit binding. eIF4A, an eIF4 complex component that acts as an ATP- dependent RNA helicase, unwinds the secondary structure of the 5' mRNA untranslated region to mediate ribosome binding. EIF4E binds to the mRNA cap structure to mediate the initiation of translation. eIF4E interacts with eIF4G, a scaffold protein that promotes assembly of eIF4E and eIF4A into the eIF4F complex. eIF4B is thought to assist the eIF4F complex in translation initiation. eIF4H induces the RNA-dependent ATP hydrolysis catalyzed by the initiation factors eIF4A and eIF4B. eIF4H was further shown to determine the initial rate and extent of eIF4A-mediated mRNA secondary structure unwinding.
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Product Notes
The Translation Initiation Complex (Catalog #AAA2550027) is an Antibody Kit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Translation Initiation Complex can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Translation Initiation Complex for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Translation Initiation Complex, Antibody Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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