Rat Type-1A angiotensin II receptor ELISA Kit | Agtr1 elisa kit
Rat Type-1A angiotensin II receptor ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
receptor for and mediator of vascular remodeling effects of angiotensin II [RGD, Feb 2006]
Uniprot Description
AT1: receptor for angiotensin II. Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. Mediates the major cardiovascular effects of angiotensin II. May play role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 17p12
Cellular Component: basolateral plasma membrane; cytoplasmic vesicle; dendrite; endomembrane system; Golgi apparatus; integral to membrane; membrane; organelle outer membrane; plasma membrane; recycling endosome; vesicle membrane
Molecular Function: angiotensin type I receptor activity; angiotensin type II receptor activity; bradykinin receptor binding; D1 dopamine receptor binding; G-protein alpha-subunit binding; peptide hormone binding; protein binding; protein heterodimerization activity; protein kinase binding; protein self-association
Biological Process: activation of JAK protein; aging; calcium-mediated signaling; dopamine biosynthetic process; drinking behavior; elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); kidney development; positive regulation of blood pressure; positive regulation of cell proliferation; positive regulation of cellular protein metabolic process; positive regulation of phospholipase A2 activity; positive regulation of receptor recycling; positive regulation of superoxide release; regulation of blood pressure; regulation of pH; regulation of vasoconstriction; renin-angiotensin regulation of aldosterone production; response to activity; response to corticosterone stimulus; response to estrogen stimulus; response to salt stress; Rho protein signal transduction; vasoconstriction
Research Articles on Agtr1
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Product Notes
The Rat Agtr1 agtr1 (Catalog #AAA9427678) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9427678 ELISA Kit recognizes Rat Agtr1. It is sometimes possible for the material contained within the vial of "Type-1A angiotensin II receptor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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