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SDS-PAGE

Annexin A3 Recombinant Protein | ANXA3 recombinant protein

Recombinant Human Annexin A3 protein

Gene Names
ANXA3; ANX3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Annexin A3; Recombinant Human Annexin A3 protein; 35-alpha calcimedin; Annexin III; Annexin-3; Inositol 1; 2-cyclic phosphate 2-phosphohydrolase; Lipocortin III; Placental anticoagulant protein III; PAP-III; ANXA3 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid containing glycerol
Sequence Positions
5-322aa; Partial
Sequence
WVGHRGTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKELKDDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMKDISQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQILYKAGENRWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIVNCVRNTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSDTSGDYEITLLKICGGD
Sequence Length
323
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

SDS-PAGE
Related Product Information for ANXA3 recombinant protein
Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate.
Product Categories/Family for ANXA3 recombinant protein
References
Five distinct calcium and phospholipid binding proteins share homology with lipocortin I.Pepinsky R.B., Tizard R., Mattaliano R.J., Sinclair L.K., Miller G.T., Browning J.L., Chow E.P., Burne C., Huang K.-S., Pratt D., Wachter L., Hession C., Frey A.Z., Wallner B.P.J. Biol. Chem. 263:10799-10811(1988)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
306
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39.9 kDa
NCBI Official Full Name
annexin A3
NCBI Official Synonym Full Names
annexin A3
NCBI Official Symbol
ANXA3
NCBI Official Synonym Symbols
ANX3
NCBI Protein Information
annexin A3
UniProt Protein Name
Annexin A3
Protein Family
UniProt Gene Name
ANXA3
UniProt Synonym Gene Names
ANX3; PAP-III
UniProt Entry Name
ANXA3_HUMAN

NCBI Description

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq, Jul 2008]

Uniprot Description

ANXA3: a calcium/phospholipid-binding protein and inhibitor of phospholipase A2, Possesses anti-coagulant properties. Cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 4q21.21

Cellular Component: axon; cell soma; cytoplasm; dendrite; membrane; phagocytic vesicle membrane; plasma membrane; specific granule

Molecular Function: calcium ion binding; calcium-dependent phospholipid binding; calcium-dependent protein binding; phospholipase A2 inhibitor activity

Biological Process: defense response to bacterium; hippocampus development; negative regulation of catalytic activity; neutrophil degranulation; organ regeneration; phagocytosis; positive regulation of angiogenesis; positive regulation of DNA metabolic process; positive regulation of transcription factor activity; response to glucocorticoid stimulus

Research Articles on ANXA3

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Product Notes

The ANXA3 anxa3 (Catalog #AAA1265366) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 5-322aa; Partial. The amino acid sequence is listed below: WVGHRGTVRD YPDFSPSVDA EAIQKAIRGI GTDEKMLISI LTERSNAQRQ LIVKEYQAAY GKELKDDLKG DLSGHFEHLM VALVTPPAVF DAKQLKKSMK GAGTNEDALI EILTTRTSRQ MKDISQAYYT VYKKSLGDDI SSETSGDFRK ALLTLADGRR DESLKVDEHL AKQDAQILYK AGENRWGTDE DKFTEILCLR SFPQLKLTFD EYRNISQKDI VDSIKGELSG HFEDLLLAIV NCVRNTPAFL AERLHRALKG IGTDEFTLNR IMVSRSEIDL LDIRTEFKKH YGYSLYSAIK SDTSGDYEIT LLKICGGD. It is sometimes possible for the material contained within the vial of "Annexin A3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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