Typical Testing Data/Standard Curve (for reference only)
Rat Type-1A angiotensin II receptor ELISA Kit | Agtr1 elisa kit
Rat Type-1A angiotensin II receptor ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to Type-1A angiotensin II receptor. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated polyclonal antibody preparation specific for Type-1A angiotensin II receptor and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain Type-1A angiotensin II receptor, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The concentration of Type-1A angiotensin II receptor in the samples is then determined by comparing the O.D. of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI Description
receptor for and mediator of vascular remodeling effects of angiotensin II [RGD, Feb 2006]
Uniprot Description
AT1: receptor for angiotensin II. Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. Mediates the major cardiovascular effects of angiotensin II. May play role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1
Cellular Component: basolateral plasma membrane; cytoplasm; cytoplasmic vesicle; cytosol; dendrite; endomembrane system; endosome; Golgi apparatus; integral to membrane; intracellular; membrane; organelle outer membrane; plasma membrane; recycling endosome; vesicle membrane
Molecular Function: angiotensin type I receptor activity; angiotensin type II receptor activity; bradykinin receptor binding; D1 dopamine receptor binding; G-protein alpha-subunit binding; peptide hormone binding; protein binding; protein heterodimerization activity; protein kinase binding; protein self-association
Biological Process: activation of JAK protein; aging; angiotensin mediated regulation of renal output; blood vessel development; brain renin-angiotensin system; calcium-mediated signaling; dopamine biosynthetic process; drinking behavior; elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); heart development; inflammatory response; kidney development; negative regulation of neuron apoptosis; positive regulation of blood pressure; positive regulation of cell proliferation; positive regulation of cellular protein metabolic process; positive regulation of cytokine secretion; positive regulation of phospholipase A2 activity; positive regulation of receptor recycling; positive regulation of superoxide release; regulation of blood pressure; regulation of pH; regulation of systemic arterial blood pressure by circulatory renin-angiotensin; regulation of vasoconstriction; renin secretion into blood stream; renin-angiotensin regulation of aldosterone production; response to activity; response to corticosterone stimulus; response to estrogen stimulus; response to salt stress; Rho protein signal transduction; vasoconstriction
Research Articles on Agtr1
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Product Notes
The Rat Agtr1 agtr1 (Catalog #AAA2882779) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2882779 ELISA Kit recognizes Rat Agtr1. It is sometimes possible for the material contained within the vial of "Type-1A angiotensin II receptor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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