Typical Testing Data/Standard Curve (for reference only)
Mouse agrin ELISA Kit | AGRN elisa kit
Mouse Agrin, AGRN ELISA Kit
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
AGRN: Plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Ligand of the MUSK signaling complex that directly binds LRP4 in this complex and induces the phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Defects in AGRN are a cause of myasthenia, limb-girdle, familial (LGM). A congenital myasthenic syndrome characterized by a typical 'limb girdle' pattern of muscle weakness with small, simplified neuromuscular junctions but normal acetylcholine receptor and acetylcholinesterase function.
Protein type: Extracellular matrix; Cell development/differentiation; Secreted, signal peptide; Cell adhesion; Secreted
Cellular Component: extracellular matrix; extracellular space; cell surface; membrane; cytoplasm; plasma membrane; integral to membrane; basement membrane; basal lamina; synapse; cell junction; sarcolemma
Molecular Function: heparan sulfate proteoglycan binding; protein binding; transforming growth factor beta binding; ATPase inhibitor activity; acetylcholine receptor regulator activity; calcium ion binding
Biological Process: positive regulation of filopodium formation; regulation of GTPase activity; regulation of protein amino acid phosphorylation; positive regulation of protein binding; neurotransmitter receptor metabolic process; multicellular organismal development; positive regulation of synaptic growth at neuromuscular junction; receptor clustering; synaptic transmission; synaptogenesis; plasma membrane organization and biogenesis; positive regulation of neuron apoptosis; protein heterotetramerization; positive regulation of transcription from RNA polymerase II promoter; regulation of synaptic growth at neuromuscular junction; positive regulation of protein amino acid phosphorylation; regulation of receptor activity; cell differentiation; neuromuscular junction development
Research Articles on AGRN
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Product Notes
The Mouse AGRN agrn (Catalog #AAA930009) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA930009 ELISA Kit recognizes Mouse AGRN. It is sometimes possible for the material contained within the vial of "agrin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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