Human alcohol dehydrogenase, iron containing, 1 ELISA Kit | ADHFE1 elisa kit
Human Hydroxyacid-oxoacid transhydrogenase, mitochondrial, ADHFE1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The ADHFE1 gene encodes hydroxyacid-oxoacid transhydrogenase (EC 1.1.99.24), which is responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues (Kardon et al., 2006 [PubMed 16616524]).[supplied by OMIM, Mar 2008]
Uniprot Description
ADHFE1: Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2- hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3- hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities. Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.1.99.24; Oxidoreductase; Mitochondrial
Chromosomal Location of Human Ortholog: 8q13.1
Cellular Component: mitochondrion; mitochondrial matrix
Molecular Function: metal ion binding; hydroxyacid-oxoacid transhydrogenase activity
Biological Process: cellular metabolic process; molecular hydrogen transport; 2-oxoglutarate metabolic process
Research Articles on ADHFE1
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Product Notes
The Human ADHFE1 adhfe1 (Catalog #AAA9337813) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337813 ELISA Kit recognizes Human ADHFE1. It is sometimes possible for the material contained within the vial of "alcohol dehydrogenase, iron containing, 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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