Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver tissue slide using MBS766400 (ADHFE1 Antibody) at dilution of 1:50)
Rabbit ADHFE1 Polyclonal Antibody | anti-ADHFE1 antibody
ADHFE1 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver tissue slide using MBS766400 (ADHFE1 Antibody) at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver tissue slide using MBS766400 (ADHFE1 Antibody) at dilution of 1:50)
Testing Data
()
Testing Data
()
Western Blot (WB)
(mouse heart tissue were subjected to SDS PAGE followed by western blot with MBS766400 (ADHFE1 antibody) at dilution of 1:1000)
Western Blot (WB)
(mouse heart tissue were subjected to SDS PAGE followed by western blot with MBS766400 (ADHFE1 antibody) at dilution of 1:1000)
NCBI and Uniprot Product Information
NCBI Description
The ADHFE1 gene encodes hydroxyacid-oxoacid transhydrogenase (EC 1.1.99.24), which is responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues (Kardon et al., 2006 [PubMed 16616524]).[supplied by OMIM, Mar 2008]
Uniprot Description
ADHFE1: Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2- hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3- hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities. Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.1.99.24; Oxidoreductase; Mitochondrial
Chromosomal Location of Human Ortholog: 8q13.1
Cellular Component: mitochondrial matrix; mitochondrion
Molecular Function: hydroxyacid-oxoacid transhydrogenase activity; metal ion binding
Biological Process: 2-oxoglutarate metabolic process; molecular hydrogen transport
Research Articles on ADHFE1
Similar Products
Product Notes
The ADHFE1 adhfe1 (Catalog #AAA766400) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADHFE1 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ADHFE1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the ADHFE1 adhfe1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADHFE1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
