Interleukin 5 Active Protein | Il5 active protein
Interleukin 5, Recombinant, Human (IL-5, BCDF-alpha, Eosinophil Differentiation Factor, EDF)
Purity
Highly PurifiedHighly Purified (98% by SDS-PAGE)
Synonyms
Interleukin 5; Recombinant; Human (IL-5; BCDF-alpha; Eosinophil Differentiation Factor; EDF); Il5 active protein
Purity/Purification
Highly Purified
Highly Purified (98% by SDS-PAGE)
Highly Purified (98% by SDS-PAGE)
Form/Format
Supplied as a lyophilized powder without additives.
Biological Activity
Human IL-5 is fully biologically active when compared to standards. The ED50 as determined by the dose-dependent proliferation of TF-1 cells is 0.15ng/ml, corresponding to a specific activity of 6x10e6 units/mg. For most in vitro applications, IL-5 exerts its biological activity in the concentration range of 0.1-10ng/ml.
Country of Origin
USA
Endotoxin Level
0.1ng/ug
Reconstitution
Reconstitute with sterile water to a concentration of 0.1-1mg/ml.
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile dH2O. Aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at
-20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
-20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Il5 active protein
Interleukin-5 (IL-5) is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils.Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant human IL-5 is a 26kD disulfide-linked homodimeric protein containing two 116 amino acid chains.
Product Categories/Family for Il5 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26.2kD
NCBI Official Full Name
interleukin-5
NCBI Official Synonym Full Names
interleukin 5
NCBI Official Symbol
Il5
NCBI Protein Information
interleukin-5; TRF; IL-5; BCGF-II; B-cell growth factor II; T-cell replacing factor; cytotoxic T-lymphocyte inducer; eosinophil differentiation factor; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil)
UniProt Protein Name
Interleukin-5
Protein Family
UniProt Gene Name
Il5
UniProt Synonym Gene Names
Il-5
UniProt Entry Name
IL5_RAT
NCBI Description
cytokine with B-cell growth factor activity [RGD]
Uniprot Description
Function: Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
Subunit structure: Homodimer; disulfide-linked.
Subcellular location: Secreted.
Sequence similarities: Belongs to the IL-5 family.
Research Articles on Il5
Similar Products
Product Notes
The Il5 il5 (Catalog #AAA650999) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Interleukin 5, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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